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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998) / Chapter Skim
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Appendix N Estimation of the Period Covered by Vitamin B12 Stores
Pages 527-530

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From page 527...
... For individuals with pernicious anemia, who cannot absorb or reabsorb vitamin Bit, the turnover rate is about 0.2 percent of the body pool or stores per clay. As inclivicluals develop various degrees of atrophic gastritis, it is possible that a turnover rate of 0.15 percent is appropriate.
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From page 528...
... REFERENCE Bozian RC, FergusonJL, Heyssel RM, Meneely GR, Darby ~J.
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From page 529...
... APPENDIX N TABLE N-2 Time in Days until Vitamin BE Threshold Is Reached 529 Turnover Rate Ratio of Initial Stores to Threshold, from Table N-1 0.1 0.15 0.2 70 4,248 2,832 2,124 60 4,094 2,730 2,047 50 3,912 2,608 1,956 40 3,689 2,459 1,844 30 3,401 2,267 1,701 20 2,996 1,997 1,498 17 2,833 1,889 1,417 16 2,773 1,848 1,386 15 2,708 1,805 1,354 14 2,639 1,759 1,320 13 2,565 1,710 1,282 12 2,485 1,657 1,242 11 2,398 1,599 1,199 10 2,303 1,535 1,151 9 2,197 1,465 1,099 8 2,079 1,386 1,040 7 1,946 1,297 973 6 1,792 1,195 896 5 1,609 1,073 805 4 1,386 924 693 3 1,099 732 549
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From page 530...
... 530 DIETARY REFERENCE INTAKES TABLE N-3 Table of Time in Years until Vitamin BE Threshold Below Which Deficiency Signs May Occur Is Reached Turnover Rate Ratio of Initial Stores to Threshold, from Table N-1 0.1 0.15 0.2 70 1 1.6 7.8 5.8 60 1 1.2 7.5 5.6 50 10.7 7.1 5.4 40 10.1 6.7 5.0 30 9.3 6.2 4.7 20 8.2 5.5 4.1 17 7.8 5.2 3.9 16 7.6 5.1 3.8 15 7.4 4.9 3.7 14 7.2 4.8 3.6 13 7.0 4.7 3.5 1 2 6.8 4.5 3.4 1 1 6.6 4.4 3.3 10 6.3 4.2 3.2 9 6.0 4.0 3.0 8 5.7 3.8 2.8 7 5.3 3.6 2.7 6 4.9 3.3 2.5 5 4.4 2.9 2.2 4 3.8 2.5 1.9 3 3.0 2.0 1.5
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Key Terms

  • body stores
  • atrophic gastritis
  • pernicious anemia
  • lowest pool
  • lower threshold

  • expected turnover
  • time body
  • normal absorption
  • develop various
  • assumed threshold

  • reabsorption rates
  • reabsorb vitamin
  • total body
  • maintain health
  • various degrees

  • daily turnover
  • sustain health
  • expected length
  • pool size
  • initial store

  • body pool
  • body counter
  • threshold level
  • threshold value
  • human requirement

  • found experimentally
  • studies suggest
  • bozian rc
  • heyssel rm
  • evidence concerning


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