Biomedical Models and Resources Current Needs and Future Opportunities (1998) / Chapter Skim
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Executive Summary
Executive Summary
Pages 1-5
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Recurrent themes in all the sources of information on which this study drew were training of whole-animal scientists, improved methods and instrumentation for physiologic assessment, infrastructure for animal-based research, databases for phenotypic information, sophisticated computer programming to handle statistical analysis of complicated data and to mode} complex biologic systems, multidisciplinary approaches, and shared resources. The committee found that expanded and stabilized competitive research funding would provide a better and more cost-effective infrastructure to enhance the utility and availability of animal models and the quality of animal-related research and laboratory animal welfare.
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Furthermore, emphasis on animal-mode} research and concerns of society about humane use of animals mandate that NIH support scientifically based rationales for the humane and efficient management of laboratory animals and for dealing with their intercurrent diseases or special medical and husbandry needs. NCRR must train people to be able to handle the concepts of integrative biology to serve the NIH research mission.
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Reliable phenotype assessment requires increased research on accurate and reliable behavioral assessment, new technology for physiologic and pathologic assessment, and new methods for analysis of complex data. ~ , ~ The study of complex diseases will require that a scientist have access to expertise in various disciplines.
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Animal populations in the nation's research facilities are increasing substantially because of burgeoning mouse populations and the increasing emphasis on integrative biology with all types of models. The resulting crowding, coupled with increased interinstitutional traffic and diminished health surveillance and diagnostic support, has created dry tinder for devastating epizootics of infectious disease among irreplaceable animal colonies.
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is of value to several scientists or for multiple purposes.
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