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2. Previous Reviews of Particulate-Matter Research Needs
Pages 25-33

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From page 25...
... Centers for Disease Control anti Prevention was held in Park City, Utah, on April 29-30, 1996, in conjunction with the Second Colloquium on Particulate Air Pollution and Health, held May ~ -3, ~ 996. The main objective of the workshop was to determine research needs related to health effects of the complex mixtures of particles and vapors commonly encountered in air.
From page 26...
... Study the health effects of coarse-mode PM~o and the ultrafine particles in nuclei-mode aerosol. · Study sensitive human subpopulations infants, the elderly, and people with pre-existing cardiopulmonary diseases.
From page 27...
... Instead, its primary purpose is to provide guidance to EPA's national research laboratories and other organizations that undertake and support research as they develop and Justin particulate-matter research plans and programs. The particulate-matter-related research needs identified by EPA included research on health effects, toxicology, atmospheric science, monitoring, modeling, and human exposure.
From page 28...
... . to generate ambient or simulated Annual and dally ambient ambient particles for laboratory background concentrations of exposure studies, diagnose the particulate matter in outdoor air effects of exposure to air pollutants Lack of animal, clinical, and for toxicology and epidemiology, and community studies of the effects for more precise and accurate associated with exposure to measurements of particulate-matter coarse-fraction particles mass, components, and parameters Uncertainties and research needs presented in the table are taken from the 1998 EPA research-needs document (EPA 1998~.
From page 29...
... below. EPA's 1996 research strategy ciocument presented a two-step planning framework for setting research priorities: · Assessment of current knowledge · Icientification of major knowlecige gaps anti key scientific questions The EPA document proposed the following criteria for ranking particulate-matter research: .
From page 30...
... EPA applied the above criteria to potential research activities and thereby identified an initial list of research priorities. The sequencing of research (i.e., the order in which research shouIc!
From page 31...
... 31 co cn En a)
From page 32...
... clearly state that the causality of adverse health effects due to PM2 5 haci not been firmly establisheci yet. On particulate-matter research priorities, the CASAC pane!
From page 33...
... 997~: Effects of long-term exposures and relative contributions of shortterm peak and cumulative exposures to long-term health outcomes Mechanisms by which particulate matter could contribute to life shortening, daily mortality and morbidity · Linkages between particulate-matter data from outdoor monitors and actual personal exposures Particulate-matter classes and physical-chemical characteristics associated with response pathways and potency Extent to which particulate matter causes health effects indepencIent of other pollutants No second rank of priorities was given by the CASAC panel. Several other research topics were mentioneci, but there was no consensus on their priorities.


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