Military Strategies for Sustainment of Nutrition and Immune Function in the Field (1999) / Chapter Skim
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VI Health and Stress
VI Health and Stress
Pages 361-362
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From page 361... ...
Chapter 18 discusses the neuroendocrine consequences of systemic infection, emphasizing the primary role of the myriad polypeptide cytokines released into the circulation by lymphocytes, monocytes, macrophages, and endothelial cells. These pluripotent mediators induce the pathophysiological response termed the acute phase reaction, which is characterized by fever; nutrient catabolism; changes in protein, carbohydrate, and lipid metabolism; and profound changes in hepatic functions and in all components of the endocrine system.
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From page 362... ...
The influence of biological rhythms on the immune system is presented in Chapter 20. Biologic rhythmic behavior has been characterized in levels of circulating white blood cells and subsets of these cells, cytokines and their inhibitors, and in the humoral immune response, although circadian time dependence of human responses to vaccination is less well documented.
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