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Appendix B: Glossary of Immunological Terms
Pages 527-536

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From page 527...
... The second phase of He immune response in that lymphocytes which recognize and bind a foreign antigen undergo initial proliferation to become cloned memory cells and to amplify the protective response. B-cells then differentiate into clones of antibody-producing plasma cells.
From page 528...
... An immunoglobulin protein produced by the immune system, designed to bind to a specific single antigen. Antibodies neutralize foreign antigens; form immune complexes; activate complement; sensitize target cells, mast cells, and basophiles; and initiate opsonization.
From page 529...
... Acting in the nature of hormones, apocrines, and/or paracrines, they allow intercellular communication and stimulate a diverse variety of responses by target cells. Cytokines include, but are not limited to, interleukins, interferons, and colony stimulating factors.
From page 530...
... Small lipid molecules derived from polyunsaturated fatty acids (contained in cellular plasma membranes) that initiate a diverse variety of cellular and physiological activities.
From page 531...
... IgE. An antibody that can sensitize mast cells and basophils during allergic reactions, causing them to release histamine and other inflammatory mediators.
From page 532...
... Interleukin. Cytokine that permits communication among white blood cells and other tissues.
From page 533...
... Major histocompatibility complex haplotypes. Genetically controlled proteins on cell surfaces that indicate its specif~c tissue type.
From page 534...
... Molecular transcription rates of both MHC classes are influenced by cytokines, thus providing an important amplification mechanism for T-cell responses. Both classes were originally recognized for their role in triggering rejection of transplanted tissues, but their larger roles in forming complexes with diverse kinds of foreign protein antigens is now known.
From page 535...
... Large, granular NK-lymphocytes can mediate antibody-dependent cellular cytotoxity as well as lysing target cells (tumor cells and modified host cells. Nonspecific immunity.
From page 536...
... T-cells recognize only short peptide sequences on intracellular protein antigens expressed on cell surface membranes; T-cells may exert a helper, suppressor, or effecter function. Thymosin.


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