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Lindane
Pages 29-32

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From page 29...
... The authors found no increase in mortality, no impairment of the central nervous syeeemor peripheral motor nerves, and co effects onECGe, liver enzymes, red and white blood cells, platelet counts, or hemoglobin. Neurologic effects were measured through electromyograms, e 1 ec troencephal ograme, ma tor~nerve c onduc tion ve ~ oc i ty, f oref inger tremors, and dexterity tracking tests.
From page 30...
... S igns o f intoxicat ion inc lude diarrhea, hypothermia, hyperirritability, incoordination, and consul ~ ions . Chronic Exposure and Care Erogenic ity Lindane was administered daily by stomach tube to male and female rats for 6 ma at 32 mg/~g or for 17 ma at 10 mg/kg (Klimmer, 1955~.
From page 31...
... to rats oral ly at 0 ~ 6.25, 12.5 ~ or 25 mg/kg on days 6-15 or pregnancy There were no observed effects on fetal body weight or survival and no increase in Intrauterine deaths or anomal ies in the groups exposed to 1 indane. Mu tagenic i ey In a dominant-lethal assay, no mutations or reproductive effects were observed (NRC, 1977b)
From page 32...
... The OSHA (1981) permissible workplace exposure ~ imit is 0.


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