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Carbon Disulfuride
Pages 41-56

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From page 41... ... Today, its most important use, occupational exposure, and injury potential occur in the production of viscose rayon fibers for textile applications and cellophane films for packaging. It is also used in pesticide production, in extraction of oils, and as a laboratory reagent (Seppalainen and Haltia, 19803. Read the entire page →
From page 42... ... Acute psychosis was a common manifestation of CS2 poisoning in rubber vulcanization plants until this process was discontinued at the end of the nineteenth century. During World War II, many cases of chronic poisoning, in which peripheral neuropathy was the leading complaint, occurred in the viscose rayon industry (Vigliani, 1954) Read the entire page →
From page 43... ... A prospective Finnish study (Hernberg et ale, 1973) of 343 male viscose rayon workers exposed at 10-30 ppm found the 5-yr mortality from coronary heart disease was almost 5 times that in a comparison cohort (other causes of death were evenly distributed) Read the entire page →
From page 44... ... Female viscose rayon workers reportedly may develop menstrual and ovarian dysfunction at concentrations of less than 3 ppm (Vasilyeva, 1973~. Infertility, threatened pregnancy terminations, and spontaneous abortions have been reported, the latter at concentrations down to 9 ppm and below (Petrov, 1969~. Read the entire page →
From page 45... ... INHALATION EXPOSURE LIMITS Exposure limits established for CS2 in various countries (Japan Assoc. Read the entire page →
From page 46... ... Retinal changes and menstrual and ovarian dysfunction reportedly occur at concentrations of less than 3 ppm (Szymankowa, 1968; Vasilyeva, 1973) , although sampling and analyt ical methods were poorly documented and control groups were sometimes lacking in these studies. Read the entire page →
From page 47... ... llS/87 In controls l9fi6 185 25-3S 62-174 S Eye burning in 96X of Sevic, 1967 rayon-production workers, 44: of cell-fiber workers; papillary light react ion abnor~1 in cell-fiber workers 1(~0 39 31-137 10 Psychomotor and peycho logic disturbances Hannis~en, 1971 125 47 124 13 Coronary heart disease in Cirle et al., 5.6X, vet 1.~% in controls 1972 33 22 40-81 ~2 Asthenosperaia , hypo- Lancran j an spe~is , teratospennia et al ., 1 969 116 50 62 5 Coroners heart disease in Liocati et al., 16. Read the entire page →
From page 48... ... workers Age Concentration, Duration: Mean or l'~g/~3 ~Mean or Range, Range, No. Or CS, H,S Or Effects Reference 36 62 29-118C 6 Periphere1 norm and CHS d~ge; conduction Tupelo c ites lowered; ERG Seppalainen abno~1 et at., 1972 _ _ 397 3S-64 29-118C - - Coronas' heart disease cause of 6~2% of deaths in Tiller et al., highly exposed vortcrs, 1968 24: in ~1~1, exposed, 142 nationally 630 20~60 13-SO -- Immunologic - act ions de creseed; job abeenteei~ increse" "shin, 196S 138 50 22~44 ~10 Artcriocclerotic changes in 30. Read the entire page →
From page 49... ... Effects Mene t rust ion i rued 1e r painful, abundant, prolong" Muscular pour diminished; ref traces ~ lcn~ Retinal degeneration, conjunctive] infl~tion, tadpole" coraea1 opacities, color~icion discurbences Menstn'stion abundant, painful, prolonged Hypot~sion; nenrous system exc itabilit~r Re ference l Ves ilg.~e 8 1 973 Vesilyeve, 1973 Szy~ouc' 1968 Ves ill, 1973 Kr~nlco et al., 1970 CThese studice based on Awe cohort of workers, exposed to carbon diculfide plus hydrogen sulfide at concenerations everecing 29-88 ag/~3 in 1960, S9-118-/~3 in 1950, and higher before 1950. Read the entire page →
From page 50... ... TAB" 1 2 Effects on Ani~le of Exposure to Carbon Dioulfide or to Carbon Diculfide Plus Hydrogen Sulfide Concentrationb ~ Species ~CS'H'S Duration Effects Reference Rae 2, 3300 6 in/d, Lethargy; lose of Seppalainen and 5 d /wk, motor control, Linnoits, 1976 10 wk; toured MC' Erich then no recoup in 12 3 d / - , wk 2 wIc Rat 2, 3300 6 in/d, Leeharg~r; lowered Seppalainen and S d/wk, but reversible Linnoile, 1976 2-S wIc MC' act 2, 000 0 2 hid Tacrese" fetal Yaroalevakii, ~ 969 through- mortality, te out cress" fertility pregnancy Rat 1, SOO O 5 hr/d, Weaknese; parely- Szendzikoucki 6 d /~c, sis, "elin and et a1. ~ 1973 1-lS mo neuron de~enere t ion; weight lose Rat 12 c 60-110 d lacreased fete1 Berilick et a1., before n~ortality, terate- 1~7S ~t ine genes i and d''ring pregnancy Rat 1.0 0.1 160 d Inflemnation of Hisickiewicz 1.0 0 bronchi; weighe et s1, 1912 O Read the entire page →
From page 51... ... T1ULE 12 (cont'd) tffeces on Ani~le of Ex~osure to Carbon Disulfide or to Carbon Disul fide Plus Rydrogen Sul fide Concentrat ionb Species CS,H,S Dureeion Effeces Reference Mouse 2,0000 2 h/d Incressed fete1 Yarosla~rekii, 1969 through- oorte1 ity; de out crecacd fertility Rabbie 780~2, 300 0 ~ h/t Peralysis ; C215 Cohen et a1., lqS~ S d /wk, d~ce; alight 38 uk liver d~gc; ~ight loss Rabbit 930 140 30 min/d, "nor~lities of Wakatsulci and 930 ~120 d bone ~rrow, Icid- Higect~ik~e, 0 140 nevs, and spleen; l9t9; Waketsuki, decsessed spe~to- 19S9 8enesis; lose of appetite; blood changes; most se ~rere witl, combined e~cposure Rat 18 0 4 mo Test~cular lesions; Gondzik, 197t (eve" no spe~togenesis other d~y ~ t Rat 78 0 2 mo Decreased number Gondzik, 1971 ( eve" of sper~tozoa; other blood vesse ls en day) Read the entire page →
From page 52... ... 1978. Sub jective and objective behavioural alterations in carbon disulphide workers. Read the entire page →
From page 53... ... 1973. Excess mortality from coronary heart disease in viscose rayon workers exposed to carbon disulfide. Read the entire page →
From page 54... ... 1969. Changes of the gonadic function in chronic carbon disulphide poisoning. Read the entire page →
From page 55... ... 1974. Microcirculation of ocular fundus in viscose rayon workers exposed to carbon disulfide. Read the entire page →
From page 56... ... 1954. Carbon disulphide poisoning in viscose rayon factories. Read the entire page →

From page 41...

... Today, its most important use, occupational exposure, and injury potential occur in the production of viscose rayon fibers for textile applications and cellophane films for packaging. It is also used in pesticide production, in extraction of oils, and as a laboratory reagent (Seppalainen and Haltia, 19803.

Carbon Disulfuride Pages 41-56

Carbon Disulfuride
Pages 41-56