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Emergency and Continuous Exposure Limits for Selected Airborne Contaminants Volume 2 (1984) / Chapter Skim
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Fluorocarbon 12
Pages 34-40

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From page 34...
... SUMMARY OF TOXICITY INFORMATION _FFECTS ON HUMANS Of 34 cases of sudden death reported by the medical examiner of Dallas, Texas, to be due to abusive, deliberate use of products that can be inhaled, 16 involved fluorocarbons (Garriott and Petty, 1980~. The victims were mainly white males aged 13-30 (mean, 18.4~.
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From page 35...
... During the course of the experiment-~hich involved tests of several other chemicals, such as trichloroethylene, carbon tetrachloride, and other fluorocarbons -- 7 of 304 control rats and 2 of 34 control guinea pigs died. Pathologic examination revealed focal necrosis in the livers of the guinea pigs.
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From page 36...
... All tissues contained measurable concentrations of nonvolatile radioactivity 24 h after exposure, but together represented less than 1% of the administered dose. It was not possible to determine whether this radioactivity was associated with metabolites of FC-12 or with unavoidable radiolabeled impurities present in the administered gas mixture.
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From page 37...
... 1966 twin EM 30~000 pan 1984 10~000 Pam 24-r EM 20~000 pan1~000 pan 90-d CEL 1, 000 pan100 Pam _~_
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From page 38...
... Newark, Delaware: E.I. du Pont de Nemours & Co., Haskel1 Laboratory for Toxicology and Industrial Medicine [3]
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From page 39...
... du Pont de Nemours & Co., Haskell Laboratory for To~cicology and Industrial Medicine.
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From page 40...
... du Pont de Nemours & Co., Haskel Laboratory for Toxicology and Industrial Medicine.
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Key Terms

  • industrial medicine
  • eye irritation
  • haskell laboratory
  • feeding studies
  • examination revealed

  • industrial hygienists
  • cardiac arrhythmia
  • investigators concluded
  • pathologic examination
  • pigs died

  • oral toxicity
  • psychomotor performance
  • food freezant
  • inhalation exposure
  • governmental industrial

  • american conference
  • brief exposure
  • exhaled air
  • chemical substances
  • exposed dogs

  • federal standard
  • performance tests
  • human psychomotor
  • control guinea
  • developed eeg

  • acute oral
  • irritation tests
  • measurable concentrations
  • intended changes
  • chez les


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