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Chlorine
Pages 5-11

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From page 5...
... Massive exposure to fumes may occur during transportation accidents, but the development of treatment procedures has resulted in low incidences of morbidity and mortality in industrial operations, as opposed to nonindustrial exposures (ACGIH, 1980; Lawson, 1981; Stecher et al., 1968; Ploysongeang et al., 1982~. EFFECTS ON HUMANS SUMMARY OF TOXICITY INFORMATION An epidemiologic study by Patil et al.
From page 6...
... Pathologic examination of rats exposed at 9 ppm showed gross evidence of infIa~matory reactions of the upper and lower respiratory tract, including hyperemia and accumulation of inflammatory material in the nasal passages. There were also various degrees of pulmonary ateJectasis or consolidation.
From page 7...
... Having reviewed available toxicity data on chlorine, the Committee believes that no compelling new information warrants revision of the previously established 60~in EEL and 90 CEL. However, on the basis of human data that suggest sensory irritation and changes in pulmonary function as results of B-h exposure to chlorine at 1 ppm, the Committee believes that the 24-h EEL should be lowered to 0.5 ppm.
From page 8...
... limit Permissible exposure (15 min.) Recommended 60-min EELa Slight irritation Men can work without interruption ACGIH TLV-TWA and OSHA standard No effects on chest ~ ray, ECG, or pulmonary-function after 30 yr of exposure a For emergency in manufacturing area and its neighborhood, in storage facilities and surrounding areas, and during transport; suggested by Zielhuis in 1970.
From page 9...
... . Barrow and Smith, 1975 Barrow _ al., 1977 Barrow _ al., 1978 6 in/d, 5 d/wk, Decreased body weight; Barrow et al., 1978 6 wk increased urinary speci fic gravity; increased alkaline phosphatase; less pulmonary inflammation than at 9 ppm 6 in/d, 5 d/wk, Decreased body weight 6 wk (females only)
From page 10...
... TLVs(R) : Threshold Limit Values for Chemical Substances and Physical Agents in the Work Environment with Intended Changes for 1983-1984.
From page 11...
... 1970. Tentative emergency exposure limits for sulphur dioxide, sulphuric acid, chlorine and phoagene.


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