Emergency and Continuous Exposure Limits for Selected Airborne Contaminants Volume 2 (1984) / Chapter Skim
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Sodium Hydroxide
Sodium Hydroxide
Pages 87-94
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From page 87... ...
The chemical acts locally, exerting a strong corrosive action whose mechanism is not known, and causes almost immediate degeneration of the tissue, which can result in rapid absorption of sodium hydroxide into the circulating system and distribution with the body water. It dissociates completely in water.
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From page 88... ...
According to the results of a study that measured tote' alkalinity of air samples in the workplace, sodium hydroxide concentrations of up to 6.7 mg/m3 in one area of the plant correlated well with subjective response data that indicated increasing respiratory irritation with increasing alkali concentration; in a second area of the plant, where sodium hydroxide content was up to 7.7 mg/m3, the correlation was poor. No explanation for the poor correlation could be found.
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From page 89... ...
Because increased temperature increases toxicity, the Committee concludes that a 1-h exposure to sodium hydroxide at 2 mg/m3 would probably produce no more than a reversible mild irritation of eyes, skin, and respiratory system. The Committee's previous recommendations for sodium hydroxide exposure limits were made in 1965 on the basis of an undocumented statement that 6.0 mg/m3 produced intolerable respiratory discomfort; the 1965 recommendation was for 10- and 30-min EELs of 4 mg/m3 and a 60-min EEL of 2 mg/m3.
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From page 90... ...
Loomis EEL 4 mg/m 30~in EEL 4 mg/m 60-min EEL 2 mg/m -901984 2 mg/m.
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From page 91... ...
Q d o V o o a o so cn v SO Cal v SO 0 0 P4 Cal ~ 0 U]
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From page 92... ...
v at: 4 ~ o If ~ o o If ~ o K o o lo: CQ C)
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From page 93... ...
TLVs(R) : Threshold Limit Values for Chemical Substances and Physical Agents in the Work Environment with Intended Changes for 1983-1984.
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From page 94... ...
1975. The rabbit as a model for evaluating skin irritants: A comparison of results obtained on animals and man using repeated skin exposures.
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