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Quantitative Relationship Between Mutagenic and Carcinogenic Potencies A Feasibility Study (1983) / Chapter Skim
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4. Summary and Conclusions
Pages 27-28

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From page 27...
... The Committee believes that such tests may well have quantitative utility, but that it would be premature to make conclusive statements now. Rather than calling for the judgment of a National Research Council study, the situation calls for more research and analys is of data.
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From page 28...
... We believe that, if a National Research Council assessment is needed, the proper time to undertake it would be when the large analyses now going on are completed. In conclusion, the Committee on Chemical Environmental Mutagens thinks that it is not now feasible for the National Research Council to study the use of short-term mutagenicity tests for quantitative prediction of human carcinogenicity.
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Key Terms

  • mutagenicity tests
  • quantitative prediction
  • animal cancer
  • current models
  • tional research

  • qualitative association
  • council assessment
  • environmental mutagens
  • additional verification
  • situation calls

  • human carcinogenesis
  • firm qualitative
  • tests arid
  • human carcinogenicity
  • cancer tests

  • require additional
  • proper time
  • chemical environmental
  • research council
  • national research

  • quantitative utility
  • human carcinogen
  • involve multiple
  • difficulty lies
  • eventual development

  • initiating event
  • dna damage
  • conclusive statements
  • multiple steps
  • care inogenicity


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