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Vaccines Against Malaria (1996) / Chapter Skim
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3 Malaria Vaccines: The Elements for Success Are Moving into Place
Pages 11-14

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From page 11...
... The opportunity now exists to select and combine the best antigens with the most promising vaccine formulation methods to induce effective, multifaceted defenses against the parasite. Workshop participants agreed that such a broad-based approach involving multiple antigens from multiple stages of the parasite will be required for the next generation of malaria vaccines.
From page 12...
... Remarkably little effort has been directed toward characterizing potential global markets for different malaria vaccines. The traditionally most attractive markets have been thought to be the military and "traveler" markets of North America and Europ~the vast emerging middle classes in South and Central America, Africa, India, and Southeast Asia, where the risk of malaria is widely recognized, have been largely overlooked.
From page 13...
... This has been effectively demonstrated by the three field trials of the experimental vaccine, Spf66, in Tanzania, The Gambia, and Thailand (Alonso et al., 1994, D'Alessandro et al., 1995~.~ Many promising field sites have already been developed withinternational funding in anticipation of near-term testing of vaccine candidates. These and other sites in development could be overseen and monitored by an extensive global malaria network of experienced researchers, foundations, and nongovernmental organizations that are anxious to participate in the process and could contribute resources that would greatly diminish the financial risk of taking vaccine candidates to field trials.
From page 14...
... Although malaria vaccines offer the greatest hope for sustained protection for the largest number of people, workshop participants acknowledged that on a global scale, malaria vaccines should be considered as one arm of a multicomponent malaria prevention and control strategy that includes mosquito control programs, the use of bednets and repellents, and chemoprophylaxis as the situation dictates.


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