Review of the U.S. Naval Medical Research Institute's Toxicology Program (1994) / Chapter Skim
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2 HISTORY OF THE TOXICOLOGY PROGRAM
2 HISTORY OF THE TOXICOLOGY PROGRAM
Pages 13-18
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From page 13... ...
With the training of physicians and others to support the Navy's new industrial Health Program at Harvard and Co{umbia universities came the beginning of a complementary industrial hygiene community, which made use of data from the general scientific literature to evaluate hazards resulting from various chemicals under varying exposure conditions. in an unrelated move, the Naval Medical Research Institute (NMRI)
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From page 14... ...
Some work was performed in-house, primarily at NMRI, and additional work was funded at universities. For instance, inhalation and dermatotoxicological research of the explosives nitroglycerin and RDX, used in underwater demolition work, was funded by the Office of Scientific Research and Development as a set of cooperative projects between the Naval Underwater Explosives Laboratory in Betterton, Maryland, and the University of Pennsylvania Medical School.
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From page 15... ...
The NTU was assigned the mission of "providing technical and specialized services in the fields of operational toxicology and health engineering as related to toxicity problems encountered aboard ships and in the design and use of new weapons; and to develop and provide biological data necessary for determining permissible exposure limits so that precautionary measures, conducive to good health practices, may be prescribed." The goal was not merely to conduct research to characterize the toxicity of materials, but to understand the specific circumstances of exposure and determine the expression of a material's intrinsic toxicity under those circumstances. In today's risk-assessment terminology (NRC, 1983)
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From page 16... ...
equivalent laboratory, the Toxic Hazards Division of the Aerospace Medical Research Laboratory (AMRL) at WrightPatterson Air Force Base (WPAFB)
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From page 17... ...
a contract to operate a large inhalation toxicology research facility, of the Toxic Hazards Research Unit, adjacent to the USAF's in-house laboratory. Approval was granted to establish the Naval Medical Research Tnstitute's Toxicology Detachment (NMRITD)
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From page 18... ...
performance deficits as the end points of neurobehavioral effects. These interests arise directly from the nature of the exposure conditions in the naval fleet and the concerns of operational commanders for the impact of chemical exposure on mission performance (or the impact of controls imposed to reduce adverse health effects)
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