Skip to main content

Review of the U.S. Naval Medical Research Institute's Toxicology Program (1994) / Chapter Skim
Currently Skimming:

3 EVALUATION OF THE CURRENT TOXICOLOGY PROGRAM
Pages 19-28

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 19...
... use these data to formulate occupational and environmental health-hazard evaluations and risk assessments, including appropriate personnel exposure limits, which address specific Navy circumstances of exposure; and (3) develop and maintain a cadre of naval personnel skilled in the discipline of toxicology and its application to health-hazard evaluation and risk assessment.
Read the entire page →
From page 20...
... That does not mean, however, that basic research should be conducted in a "vacuum"; rather, it should be focused in areas that address specific toxicological needs. For example, studies on the molecular effects of a class of chemicals could be used to identify hiomarkers of exposure.
Read the entire page →
From page 21...
... reorienting research with a consistent goal of publishable results. Personnel issues are further discussed below in the section "Constraints on Executing Scientific Program." The subcommittee applauds incorporating triservice planning as part of NMRITD's toxicology program and encourages expansion of joint efforts in toxicological research on problems common to all branches of the armed services.
Read the entire page →
From page 22...
... Effectiveness of Current Research The triservice combustion toxicology program and the pathology laboratory program were two areas in which the research was viewed as effective in addressing the Navy's problems in the area of toxicology. Both were judged capable of providing a wide range of support for toxicology and investigative efforts.
Read the entire page →
From page 23...
... Pursuit of basic research projects designed to obtain fundamental knowledge would be enhanced by collaboration with academia, other government laboratories, and industry. Constraints on Executing the Scientific Program The subcommittee identified four constraints that affect the ability of NMRITD to execute its scientific program: staffing, space and facilities, equipment, and the funding cycle.
Read the entire page →
From page 24...
... and methods of applying research results to health-hazard evaluation and risk assessment. This career track should lead into senior program management and technical expert applications, which would permit the Navy to take advantage of specialized capabilities to integrate the toxicology program into broader Navy strategic plans and programs.
Read the entire page →
From page 25...
... Lack of adequate space makes experimentation difficult for certain types of research e.g., cell and tissue culture and use of radiolabeled materials, both of which require dedicated space. The heating, ventilation, air conditioning, and temperature and humidity control systems are inadequate for inhalation and general toxicity studies, as are the chemical handling hoods, which are supported by a single exhaust system and which present potential safety problems.
Read the entire page →
From page 26...
... RECOMMENDATIONS FOR THE CURRENT TOXICOLOGY PROGRAM The subcommittee recommends the following changes in NMRITD's current toxicology program: · The toxicology program should be expanded to Place greater emphasis on predicting toxicity of materials used in Navy operations. Place greater emphasis on developing permissible exposure limits for exposure scenarios encountered by Navy personnel.
Read the entire page →
From page 27...
... · Funding: It is extremely difficult to build a quality research program with the current l- to 2-year funding cycle. Therefore, serious consideration should be given by the appropriate administrative office within the Navy to coordinate and improve funding procedures for NMRTTD.
Read the entire page →

Key Terms

  • current toxicology
  • applied toxicology
  • funding cycle
  • subcommittee recommends
  • civilian scientists

  • toxic chemicals
  • staying abreast
  • quality research
  • effects detected
  • career track

  • proper mix
  • funding procedures
  • address specific
  • exposure limits
  • administrative office

  • navy personnel
  • scientific studies
  • personnel skilled
  • appropriate administrative
  • pathology laboratory

  • toxicology subspecialties
  • program execution
  • serious consideration
  • subcommittee identified
  • addressing actual

  • questions pertaining
  • career plan
  • naval personnel
  • joint efforts
  • evaluate current


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.