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6. Assessing the Likely Utilization of New Vaccines
Pages 76-81

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From page 76...
... However, predicting future utilization rates of vaccine candidates is difficult, even for a relatively homogeneous population, because vaccine utilization depends on many interrelated and complex factors. These factors include: · vaccine availability · the capacity of the health care system to deliver the vaccine to potential recipients · the effects of statutory interventions, such as the U.S.
From page 77...
... Factors influencing a pharmaceutical company's willingness to manufacture a vaccine include: · profitability in public or private sale, which is affected by market size and composition (e.g., ability to pay) , public health initiatives, patentability or status as sole supplier, and provider and lay acceptance · legal concerns, particularly costs associated with vaccine injury compensation liability, which is a major issue in the United States · technical difficulty of production and of distribution (in a manner that ensures potency)
From page 78...
... Several studies of voluntary vaccine utilization in developing countries suggest that the factors determining relevant health decisions in the developing world are similar to those postulated in the HBM (Adeniyi, 1972; Azurin and Alvero, 1971; Hingson, 1974; Hingson and Lin, 1972; Hsu, 1955; Lin et al., 1971; Ogionowo, 1973; Ristori, 1969~. It is important to recognize, however, that local perceptions of disease and health care are molded by social, educational, and economic conditions radically different from those in the United States.
From page 79...
... Also, in many areas, health care systems cannot routinely reach large portions of the target population. In some countries, successful periodic mass immunization campaigns have been conducted, utilizing the mass media and personnel with minimal health training.
From page 80...
... Because delivery of vaccines would probably be achieved through the WHO-EPI, the committee assumed for the analysis that utilization rates of vaccine candidates would be uniform across target populations. (Actual decisions about whether to incorporate specific vaccines into EPI should be based on local assessments of disease burdens, resources, and other considerations.)
From page 81...
... New Vaccine Development: Establishing Diseases of Importance in the United States. Washington, D.C.: National Academy Press.


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