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II. OVERALL IMPRESSIONS
Pages 13-18

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From page 13...
... The committee views it as essential that the model calculations clearly demonstrate not only consistency and an appropriate choice of parameters, but also satisfactory agreement with past measurements and observations, a reasonable representation of actual exposure conditions of "real" people, and a capacity to serve a suitable basis for epidemiologic studies including the planned Hanford Thyroid Disease Study.
From page 14...
... That description is of questionable credibility for the whole period and of doubtful value, considering the lower rates of atmospheric and aquatic transport and movement in the food chain. The absence of detailed discussion of model validation for the various pathway descriptions raises the question of agreement between calculation and measurement, the method of selection of the many parameters involved, and the reality of the ranges of uncertainty for each dose descriptor and the graphically presented dose values.
From page 15...
... In a report intended for public consumption, the relevance of such a wide range requires some explanation to provide perspective. The committee recommends that the diagrams include bars to show the 5th to 95th percentile results rather than the entire range.
From page 16...
... A tabulation of pathways considered and reasons for rejection might be useful. Similarly, it is important to indicate the outcome of any studies on particular pathways or exposure conditions that were undertaken in response to public inquiries, political priorities, or concerns regarding selected target groups, such as American Indian tribes or migratory workers.
From page 17...
... By concentrating on doses to individuals, the reports imply that each individual can, through his or her personal dose estimate, predict their chances of developing a cancer as a result of their exposure. It would be beneficial to provide estimates of the total number of excess cancers and cancer deaths that might be expected in order to provide an estimate of the societal impact of the exposure doses.
From page 18...
... Dose-distribution estimates must be suitable as a basis for epidemiologic assessments, so appropriate demographic data should be developed in parallel. Accordingly, the committee recommends that the HEDR study focus more on the dose to real people and the use of realistic, not worst-case, exposure pathways.


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