Toxicity of Alternatives to Chlorofluorocarbons HFC-134a and HCFC-123 (1996) / Chapter Skim
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1 INTRODUCTION
1 INTRODUCTION
Pages 7-12
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From page 7... ...
in large amounts in refrigeration, metal and electronics cleaning, mobile air conditioning, ancI steril ization. Until recently, the Halon gases were used extensively in fighting fires and were the major components of fire extinguish.
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From page 8... ...
up coming restrictions on their availability, industry has been search ing for substitute chemicals that will perform the same functions as the CFCs and BFCs without adversely affecting human health or the environment. Two of the chemical classes under consideration for replacing CFCs are hyctrochiorofluorocarbons (HCFCs)
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From page 9... ...
Similarly, the Air Force has requested that the NRC evaluate the adequacy of the ~ min EEGL proposed by Air Force toxicologists for exposure to HCFC 123. HCFC 123 is a proposed substitute for Halon 1211, the fire extin guishant currently user!
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From page 10... ...
The EEGL for a substance represents the subcommittee's judgment based on evaluation of experimental anti epiclemiological ciata, mechanisms of injury, anti, when possible, operating conditions in which emergency exposure might occur, as well as consideration of DOD goals and objectives. Acute toxicity is the primary basis for establishing an EEGL.
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From page 11... ...
Generally, EEGEs have been developecI for exposure to single substances, although emergency exposures often involve complex mixtures of substances and thus have a potential for toxic synergism. In the absence of other infor mation, guidance levels for complex mixtures can be developer!
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From page 12... ...
Sup porting documentation on HCFC 123 is contained in Appendix A and attachments ~ 4. That information was generated either by the Air Force toxicologists or the manufacturer of HCFC 123.
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