Health Effects of Permethrin-Impregnated Army Battle-Dress Uniforms (1994) / Chapter Skim
Currently Skimming:
5 DERMAL AND OCULAR TOXICITY OF PERMETHRIN
5 DERMAL AND OCULAR TOXICITY OF PERMETHRIN
Pages 57-66
The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.
From page 57... ...
Human Data Little information exists on workers who manufacture permethrin. In a study of six Swedish forestry workers who handled seedlings immersed in a 2% aqueous solution of permethrin (Kolmodin-Hedman et al., 1982)
|
From page 58... ...
Although substantial exposures and absorption occurred, as shown by urinary excretion studies, no adverse health effect could be attributed to permethrin exposures in this group. Among 17 civilian volunteers exposed to I% permethrin (cis/trans ratio, 25:75)
|
From page 59... ...
Of the cynical trials to date, several provided details of possible health effects attributable to permethrin. All published studies made some mention of the presence or absence of side effects, and some provided a systematic account of their methods and findings; these studies are summarized in Table 5-~.
|
From page 60... ...
60 cn v, as cot o Pa cd 4~ ~3 .s an O O .
|
From page 61... ...
In practice, the reported incidence of allergic skin reactions has been extremely low-about two patient reports for every 500,000 units distributed (Taplin and Meinking, 1993)
|
From page 62... ...
of six New Zealand White rabbits (three of each sex) once a day for 16 days, a slight erythema appeared, which correlated with increased cutaneous blood flow.
|
From page 63... ...
did not produce dermal irritation or sensitization in groups of 10 male guinea pigs when applied as a 25% dispersion in petrolatum. The positive control, DNCB (5 % wt/vol)
|
From page 64... ...
. Skin treated with the positive control solution and irradiated exhibited a greater irritation reaction than did nonirradiated skin.
|
From page 65... ...
However, several subjects described a transient burning, stinging, or itching sensation. The results of the photochemical irritation studies described above showed that permethrin does not cause phototoxicity (photochemical irritation)
|
Key Terms
This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More
information on Chapter Skim is available.