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8 IMMUNOTOXICITY OF PERMETHRIN
Pages 77-78

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From page 77...
... , permethrin at a concentration of approximately lO-s to lo-6 M inhibited the mitogenic response of murine immune lymphocytes. Although permethrin inhibited the mitogenic response of murine lymphocytes in vitro, mitogenic responses in in vitro exposures do not represent functional immunity, nor do they simulate in vivo reactions.
From page 78...
... Immunotoxicological investigations need to be performed in laboratory animals to ascertain the immunotoxic properties, if any, of permethrin in mammalian species. These studies should follow the guidelines presented in the National Research Council's report Biologic Markers in ·mmunotoxicology (NRC, 1992~.


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