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4 Introduction
Pages 65-68

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From page 65...
... Ideally, identifying the air contaminant or class of contaminants implicated in producing adverse health or comfort effects is essential in designing an a~r-monitoring program. In practice, however, it is often necessary to monitor a class of contaminants (for instance, total mass of respirable particles)
From page 66...
... In epidemiologic studies of air contaminants, it is important to specify exposure to specific particulates or gases on a time scale corresponding to the health or comfort effect sought. The impact of exposure to an air contaminant should, ideally, be evaluated in terms of the biologic dose of the contaminant or its metabolites received by the target tissue.
From page 67...
... to provide a simple categorization of exposure levels, such as exposed versus unexposed or none versus low versus high. Questionnaires have been used to categorize subjects' exposure to ETS in all studies of risk of chronic lung disease reported to date.
From page 68...
... Efforts to modify or eliminate exposures to ETS must focus on the factors that control the concentrations in the physical environment, since these factors result in the exposure that relates to the adverse health or comfort effect. REFERENCE National Research Council, Committee on the Epidemiology of Air Pollutants.

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