Vitamin Tolerance of Animals (1987) / Chapter Skim
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12 Biotin
12 Biotin
Pages 70-73
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From page 70... ...
NUTRITIONAL ROLE Dietary Requirements of Various Species Although animals have a metabolic requirement for biotin, it is not yet established that it is a dietary essential for all species, due to widespread intestinal synthesis. The administration of certain sulfa drugs can be used to induce biotin deficiencies.
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From page 71... ...
A biotin level of 0.1 mg/kg of diet produced 0.2 ,ug/g of yolk weight; a biotin level of 0.34 mg/kg of diet produced 0.6 Agog of yolk weight. No adverse effects of the higher biotin levels were noted.
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From page 72... ...
72 ¢ E E W ~C =~ .= ¢ ~ of C ° hobo ~ ¢} US - 1 ~ E In C: ~ oo 3 ~ ¢ 4 o ~ E ~ E a a w U)
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From page 73... ...
No significant differences were noted in implantation rate, number of resorption sites, fetal weight, placental weight, or ovarian weight. PRESUMED UPPER SAFE LEVELS Insufficient data are available to support estimates of the maximum dietary tolerable levels of biotin.
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