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Vitamin Tolerance of Animals (1987) / Chapter Skim
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13 Vitamin B12
Pages 74-76

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From page 74...
... A synthetic form is commonly used as a feed supplement. NUTRITIONAL ROLE Dietary Requirements of Various Species All nonruminant species require dietary sources of vitamin Bit.
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From page 75...
... Effect Growth rate similar; no adverse effects Concentration greatest in placenta 7.5 fig, no adverse effects; 15 ,ug, 20~o mortality; 30 fig, 100% mortality 100(70 Mortality No mortality or adverse effects on growth No mortality or adverse effects Reference Schaefer et al., 1949 Denker, 1983 Traina, 1950 Traina, 1950 Winter and Mushett, 1951 Winter and Mushett, 1951
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From page 76...
... PRESUMED UPPER SAFE LEVELS Insufficient data are available to support estimates of the maximum dietary tolerable levels of vitamin Bit. Data from a single chick study suggest that 3 times the vitamin By requirement of that species can be included safely in the diet, however.
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Key Terms

  • single dose
  • central cobalt
  • cobalt atom
  • hundred times
  • nonruminant species

  • dietary levels
  • intrinsic factor
  • succinyl coa
  • administered doses
  • injected pregnant

  • animal feeds
  • animal species
  • usual form
  • administered intraperitioneally
  • single reaction

  • cobalamins principally
  • dietary sources
  • resulting defect
  • based solely
  • require dietary

  • gastric juice
  • macrocytic hyperchromic
  • methylmalonic acid
  • propionic acid
  • mouse studies

  • factor released
  • body load
  • radiolabeled vitamin
  • tissue storage
  • toxic effects


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