Committee on Military Nutrition Research Activity Report 1994-1999 (1999) / Chapter Skim
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G: Conclusions and Recommendations from the Brief Report: Pennington Biomedical Research Center September 1996 Site Visit
G: Conclusions and Recommendations from the Brief Report: Pennington Biomedical Research Center September 1996 Site Visit
Pages 163-184
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From page 163... ...
Appendix G Conclusions and Recommendalrions from l;he Brief Report; Pennington Biomedical Research Center September 1996 Site Visit Submittea' September 1996
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From page 165... ...
It is the committee's judgment that as the PBRC receives new directives from its military sponsor, the center now has the staff and expertise to develop appropriate programs utilizing its individual laboratory units as interactive modules. The PBRC has noted that the center's military nutrition research goals for 1997-2002 are: to increase publications, patents, and technology transfer; to increase collaboration with Army scientists; to increase the integration of specific tasks and laboratories; to conduct a military nutrition symposium every other year; and to invite a "military nutrition visiting professor" six times yearly for consultation and peer review.
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From page 166... ...
Army grant is to provide nutrition laboratory research support to the military nutrition research program at USARIEM. This support includes performing biochemical assessment of nutritional status and performing analyses of nutrient and biochemical substances in foods used in military rations ~ Please note that the task numbers correspond to the task numbers assigned in the preproposal (see Appendix II)
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From page 167... ...
The laboratory houses state-of-the-art equipment and a well-trained staff. It is evident by the level of clinical laboratory support provided to USARIEM in conducting military nutrition research that this laboratory is vital to the DoD nutrition research program.
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From page 168... ...
The committee recommends that efforts associated with expanding the capability of chemical analysis of food composition be restricted to obtaining data that are not available from other reliable sources and which directly support metabolic unit studies. Finally, the committee recommends continued financial support of the Clinical Research Laboratory, as this laboratory provides services to the Stable Isotope Laboratory, Menu Modification/Enhancing Military Diets Project, and the Nutrient Database Integration Laboratory (see Tasks 1, 2, 6, and 7~.
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From page 169... ...
In addition, Dr. DeLany and coworkers should continue to assist the Army with developing experimental designs that ensure the optimal execution of studies using doubly labeled water as well as other stable isotopes.
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From page 170... ...
Rodent models have been developed to evaluate the impact of nutritional interventions for their potential to moderate or prevent stress-induced neurochemical changes and their subsequent behavioral deficits. Many models have been evaluated, including a model of acute stress; a model of chronic stress induced by sleep deprivation or by restraint; chronic mild stress induced by exposure to a random mild stressor for several weeks; and an alternate model to study stress and retention utilizing a fixed-ratio training schedule in operant chambers.
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From page 171... ...
Recommendations The committee recommends that the investigators seek expert help in stress, pharmacology, and formulation of research diets to assist in the identification of appropriate pharmacologic and nutritional models and interventions. This may be accomplished in conjunction with the PBRC's 1997-2002 research goals as presented at the site visit, one of which is to bring in visiting professors; it may also be accomplished by holding a 1-day meeting specifically dedicated to examining animal models of stress, that have been used successfully in measuring stress.
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From page 172... ...
Recommendations The CHAR feels that it would not be in the Army's best interest to continue to provide support for the conduct of the sleep-deprivation studies within the Sleep Laboratory. Task 6: Menu Modification/E chancing Military Diets Project and Task 7: Nutrient Database Integration Laboratory Project Summary In its preproposal, the PBRC has divided the original Menu Modification Project into two projects.
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From page 173... ...
Based on interviews with Army personnel, PBRC investigators have proposed a list of modified recipes for testing, with an emphasis on ethnic foods and new breakfast items. The new task proposed for the Nutrient Database Integration Laboratory involves the development and expansion of activities to assist the Army in estimation of the nutrient content of recipes and menus, as well as in the evaluation of dietary intake records from field studies conducted by USARIEM.
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From page 174... ...
The PBRC nutrient database has been validated against the University of Minnesota Nutrition Coding Center database, and also has been utilized in two large, NIH-sponsored multicenter clinical trials. Specific Comments, Concerns, and Questions for Tasks 6 and 7 Since it was demonstrated that approximately 50 percent of the food intake of personnel in Army facilities represents food consumed outside of military dining halls, it is questionable whether the development of low fat menus alone
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From page 175... ...
In addition to menu modification, the committee strongly recommends to the PBRC and to the Army the use of nutritional education approaches such as those in the Army's Performance Power nutrition education program in order to achieve dietary intakes that meet military dietary goals. The CMNR believes the Menu Modification/Enhancing Military Diets Project is relevant to the Army mission and provides valuable support to USARIEM.
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From page 176... ...
General Comments for Tasks 5 and 8 The committee believes that the integration of Tasks 5 and 8 is highly desirable but suggests that the objectives of both tasks would best be accomplished in human subjects. The superb PBRC Metabolic Unit would easily allow these performance studies to be conducted so that studies of balance, body composition, protein turnover, energy metabolism (these last three using stable isotopes)
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From page 177... ...
After 4 weeks, changes in bone resorption markers are similar to those seen in more conventional human models after 4 months. General Comments The Metabolic Unit facility, in conjunction with the Stable Isotope Laboratory and Clinical Research Laboratory, provides an outstanding opportunity to control dietary interventions and physical conditions and to perform analyses of related metabolic parameters so that specific questions of
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From page 178... ...
The rationale presented was that use of an animal model would be less expensive than experiments involving the Metabolic Unit. However, in listening to the proposals to evaluate work performance, diet, and immune function, the CMNR believes that much of the proposed work could be conducted better and with more direct application to the needs of the military using human subjects (see Tasks 5 and 8~.
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From page 179... ...
The committee recommends continued support for and integration of the Clinical Research Laboratory, Stable Isotope Laboratory, Menu Modification/Enhancing Military Diets Project, and Nutrient Database Integration Laboratory at a level consistent with USARIEM needs. Experimental studies utilizing the technique of doubly labeled water as well as the incorporation of studies within the Metabolic Units Project employing isotopes to evaluate nutrient utilization should receive high priority in developing projects of interest to the Army.
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From page 182... ...
The excellent dedication of the entire FNB staff has made the desired fast reporting on this project review a reality. Also, the chair continues to be extremely pleased with the dedication, cooperation, and excellence of the critical review that the members of the CMNR bring to this activity in support of the military nutrition research
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From page 183... ...
Army Ranger Training Class 11/91. A brief report of the Committee on Military Nutrition Research, Food and Nutrition Board.
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