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Toxicity of Military Smokes and Obscurants Volume 3 (1999) / Chapter Skim
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Appendix G: Disperse Red 11
Pages 83-87

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From page 83...
... One study instilled a suspension containing disperse red ~ ~ to determine its retention in the lungs of rats. The study determined that disperse red ~ ~ is rapidly absorbed into the blood with only 66% of the instilled dose remaining at 5 min and 3.5% remaining at 24 hr (Henderson et al.
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From page 84...
... Those studies are summarized in Table Go-. Acute-toxicity studies using two dye lots of disperse red IT exposed female rats by either the oral or dermal routes and established the lethal dose for 50% of the animals (LD50)
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From page 87...
... 1986. Dermal, Eye, and Oral Toxicological Evaluations, Phase IV Report with Disperse Red 11, Disperse Blue 3, Solvent Red 1, and Red and Violet Mixtures.
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Key Terms

  • mouse lymphoma
  • studies using
  • ovary cells
  • chinese hamster
  • hamster ovary

  • guanine phosphoribosyl
  • increased frequency
  • dye lot
  • hypoxanthine guanine
  • lymphoma assay

  • mutant frequency
  • toxicity studies
  • allergic contact
  • mutagenicity studies
  • irritation study

  • phosphoribosyl transferase
  • lymphoma cells
  • body weight
  • contact dermatitis
  • dermal routes

  • bacterial assays
  • six females
  • disperse dyes
  • effects research
  • suspension containing

  • female rats
  • study conducted
  • mildly irritating
  • mixed results
  • anthraquinone dyes


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