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Executive Summary
Pages 1-6

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From page 1...
... Social scientists are demonstrating the significance of cultural supports and life experiences in shaping cognitive content and processes over the life span. All these scientific developments are making possible new understandings of how normal processes of aging affect cognitive functioning and new interventions to maintain cognitive performance in older people.
From page 2...
... A research initiative on neural health should consist of elements addressed to each of four major goals: developing quantitative functional and performance indicators, including behavioral tests, for neuronal health and neuronal dysfunction; identifying factors that affect neural health during the aging process, especially including imbalances in homeostatic processes, such as apoptosis, inflammation, and oxidative activity; devising interventions for the maintenance of healthy neu
From page 3...
... The NIA should undertake a major research initiative to understand the effects of behavioral, social, cultural, and technological context on the cognitive functioning and life performance of aging individuals and to build the knowledge needed to intervene effectively in these contexts to assist individuals' functioning and performance. Current research indicates that aging impairs cognition in some tasks but spares it in others.
From page 4...
... Research under the initiative should emphasize three method-based research strategies for understanding the aging mind: relating high-resolution measures of neural functioning to measures of cognitive functioning; elaborating theory-based and mathematical models; and conducting and analyzing largescale, multivariate studies. Achieving the goals of these research initiatives will require, in addition to financial support for research, special efforts to meet the needs for interdisciplinary research, provide specific infrastructure, and increase collaboration between the NIA and other agencies.
From page 5...
... 5c. The NIA should support the capacity for using brain imaging data in the following ways: supporting a consensus conference to develop standard procedures for collecting and reporting human brain imaging data, specifically including MRI data, on brain-behavior relationships in aging; and working with other institutes at the National Institutes of Health to establish a monkey brain imaging facility with TORI capability at the National Institutes of Health and to support a few similar centers elsewhere.
From page 6...
... 6 THE AGING MIND 6. The NIA should seek additional opportunities to participate with other institutes such as the National Institute of Mental Health, the National Institute of Neurological Disorders and Stroke, and the National Eye Institute to develop initiatives in neuroscience and cognitive aging as a way to increase the power of its research investments.


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