Skip to main content

DPT Vaccine and Chronic Nervous System Dysfunction A New Analysis (1994) / Chapter Skim
Currently Skimming:

History and Background
Pages 4-4

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 4...
... No conclusions or other official IOM report resulted from the workshop; however, a summary of the discussion was published by two of the participants (Marcuse and Wentz, 19901. The SONIC project ended in 1990, with a finding that pilot study data did not show a statistically significant increased risk of serious acute necrologic illness following vaccination against pertussis; the investigators noted that the study "had limited power to detect significant elevations of risk for individual conditions." The IOM committee reviewed the results of the pilot project and recommended that the CDC not attempt a more definitive study, primarily for reasons of epidemiologic feasibility and the likelihood that even a large,
Read the entire page →

Key Terms

  • epidemiologic study
  • definitive study
  • cdc contract
  • recommended relatively
  • significant elevations

  • investigators noted
  • sonic protocol
  • following vaccination
  • significant increased
  • individual conditions

  • illness following
  • minor changes
  • cdc requested
  • pilot project
  • increased risk

  • major methodologic
  • limited power
  • sonic project
  • relatively minor
  • iom sponsor

  • serious acute
  • detect significant
  • methodologic flaws
  • sonic investigators
  • pilot epidemiologic

  • epidemiologic feasibility
  • iom appointed
  • study data
  • pilot study
  • committee reviewed


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.