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1 Introduction and Background
Pages 21-28

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From page 21...
... . This report reviews the scientific literature regarding the uses of clietary reference stanciarcis and their applications, and provides guidance on the application of DRIs to assess the nutrient intakes of groups and inclivicluals.
From page 22...
... This approach differs from that of the joint World Health Organization and Food and Agriculture Organization Expert Consultation on requirements of vitamin A, iron, folate, and vitamin BE (FAD/WHO, 1988) , which recommencleci both a basal requirement (the amount of nutrient neecleci to prevent clinically detectable impairment of function)
From page 23...
... . Like the former RDAs and RNIs, each type of DRI refers to the average ciaily nutrient intake of apparently healthy inclivicluals over time, although the amount may vary substantially from clay to clay without ill effect in most cases.
From page 24...
... , the risks of inadequacy and of excess are both close to 0. At intakes above the UL, the risk of adverse effects increases.
From page 25...
... As intake increases above the UL, the potential risk of adverse effects increases. The term tolerable intake was chosen to avoid implying a possible beneficial effect.
From page 26...
... In contrast, the AI is an experimentally derived or observed mean intake that appears to maintain a specific criterion of adequacy in a group of apparently healthy people. Therefore, by definition, the RDA incorporates only the estimated variability in requirements, where
From page 27...
... and ULs for apparently healthy persons of all ages and both genders in various physiological states is ambitious. Ideally, ciata from the target population on intakes at various levels and the functional effects of these intakes would be available.
From page 28...
... can be used to estimate the prevalence of potential risk for adverse effects in groups. Specific guidance with examples on appropriate applications of the DRIs for group assessment purposes is provicleci in Chapter 7the methodological approaches clescribeci in Chapters 4, 5, and 6 are applied to some of the specific uses of clietary reference stanciarcis reported in Chapter 2.


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