Skip to main content

SMART Vaccines: Strategic Multi-Attribute Ranking Tool for Vaccines

Watch the video SMART Vaccines Trailer
An overview video of the program in action
Download Software SMART Vaccines Software
Download, User
Instructions, and Screenshots
Read/Download Related Reports Reports: Ranking Vaccines
Read Online or
Download PDF
See additional tools and resources Additional Resources
Get data tables

A decision-
support tool to assist in prioritizing vaccine development.

SMART Vaccines—Strategic Multi-Attribute Ranking Tool for Vaccines—is a pioneering decision-support software tool from the Institute of Medicine being developed (in collaboration with the National Academy of Engineering) to help prioritize new vaccines for development. This software tool has been developed over three phases, discussed in three reports: Ranking Vaccines: A Prioritization Framework (2012), Ranking Vaccines: A Prioritization Software Tool (2013), and Ranking Vaccines: Applications of a Prioritization Software Tool (2014).

Copyright © 2015 National Academy of Sciences. All rights reserved. To request permission to reprint or reuse this content in a publication or other media, contact

SMART Vaccines Video Overview

SMART Vaccines
Emerging new infections and re-emerging diseases require new vaccines for prevention. It is difficult to decide which new vaccine to develop, especially when making investment decisions in vaccine development. Thus, decision-makers working under constrained resources need tools that can be suitable within their environment and serve as an aid in vaccine prioritization efforts.

An Introduction to SMART Vaccines
IOM President, Dr. Harvey Fineberg, introduces SMART Vaccines.

SMART Vaccines Software | File Download and Instructions | Screenshots

SMART Vaccines
.exe file for Windows

System Requirements:
Windows (XP or above)

Last Updated:

SMART Vaccines Download Instructions:

Click the Download SMART Vaccines button on the left and save the smart_vaccines_1-1.exe (version 1.1) file to your computer. It may take several minutes to install the software depending on your computer configuration.

SMART Vaccines User Instructions:

  1. The software is designed to self-guide the user through the prioritization process.
  2. Navigation buttons at the top right of the screen orient the user to the place they are in the process.

Need help? Get in touch with us.

SMART Vaccines Screenshots
Click image to enlarge

Screen view 1

Screen view 1

Screen view 1

Screen view 1

Screen view 1

Related Reports

Ranking Vaccines - Phase III

Ranking Vaccines: Applications of a Prioritization Software Tool: Phase III: Use Case Studies and Data Framework

Ranking Vaccines: Applications of a Prioritization Software Tool (2014) demonstrates the practical applications of SMART Vaccines through case scenarios in collaboration with the Public Health Agency of Canada, New York State Department of Health, Serum Institute of India, and the Mexico Ministry of Health.

Ranking Vaccines - Phase I

Ranking Vaccines: A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System

Ranking Vaccines: A Prioritization Software Tool (2013) discusses the methods underlying the development, validation, and evaluation of the significantly redesigned SMART Vaccines 1.0. It describes how SMART Vaccines should--and, just as importantly, should not--be used. The report provides a guiding principle and a set of strategies for future enhancements for SMART Vaccines as well as for ideas for expanded uses and considerations and possibilities for the future.

Ranking Vaccines - Phase I

Ranking Vaccines: A Prioritization Framework: Phase I: Demonstration of Concept and a Software Blueprint

Ranking Vaccines: A Prioritization Framework (2012) describes a multi-attribute utility model to help decision makers with new vaccine prioritization. It also discusses an associated software blueprint called SMART Vaccines Beta and offers ideas for how such a software tool could be employed as a decision support system.

PDF Summary | IOM Report Page

Additional Resources

Download Data

Included with SMART Vaccines 1.0 are Microsoft Excel files that contain data for the test vaccine candidates. The tables document the calculations and sources used to derive the necessary information. These data table provide the users guidance in ways to gather and estimate data from various sources.

There are two datasets: 1) health burden, and 2) costs associated with the disease. The Phase II report includes a detailed explanation of the methodology used to collect and estimate parameters for the software.