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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Suggested Citation:"1 Rodents." National Research Council. 1979. Animals for Research: A Directory of Sources, Tenth Edition and Supplement. Washington, DC: The National Academies Press. doi: 10.17226/1674.
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Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

RODENTS Footnote symbols are used consistently in this section, as follows: * *.* or indicate companies holding registered trademarks; 11 indicates timed and untimed pregnant females available; § and @ are used for footnotes other than those listed above. The terms used in this section are defined in the "Terms and Defin- itions" section and are abbreviated as follows: Microbiological status: C conventionally reared BR barrier reared or specific pathogen free (SPF) Rearing by means other than natural mother: f fostered DF defined flora OF germfree GN gnotobiote fh fostered by hand In the "Mice" section, a letter and two numbers in brackets, e.g., [J72], following an fh subscript indicates the place and year of hysterectomy derivation of the substrain. Surgical modifications available: adr adrenalectomy cas castration hyp hypophysectomy nep unilateral nephrectomy thy ova ovariectomy used: pan pancreatectomy pare parathyroidectomy thr thyroidectomy thymectomy In the outbred "Guinea Pigs" section, the following color codes are A albino 1 C colored

2 RODENTS In the "Hamsters" section, pathology and life span information has been included in an attempt to make the listings additionally useful for research purposes. OUTBRED STOCK INFORMATION BREED OR STOCK DESIGNATION: "International Standardized Nomenclature for Outbred Stocks of Laboratory Animals," International Committee on Labora- tory Animals (ICLA) Bulletin, No. 30, March 1972, has been used in desig- nating these animals. Copies of this bulletin are available from the Institute of Laboratory Animal Resources (ILAR), 2101 Constitution Avenue, N.W., Washington, D.C. 20418. . Letters preceding the colon designate the supplier/breeder code consisting of a capital and two or three lower case letters. · Capital letters following the colon are used by a breeder to identify his stock. · Letters in parentheses denote origin of stock. · Subscript symbols (shown on previous page) indicate rearing by means other than natural mother. MICROBIOLOGICAL STATUS: Abbreviations have been listed previously. Ex- planations are provided in the "Terms and Definitions" section. COLONY CLOSED 19 the colony. __ Year after which no new animals were introduced into SURGICAL MODIFICATIONS AVAILABLE: Surgical modifications of animals that can be provided by suppliers by arrangement. listed on the previous page. The abbreviations used are CODE: Code designations for suppliers. Names, addresses, and phone num- bers for suppliers are listed in the final section of the book. INBRED STRAIN INFORMATION STRAIN DESIGNATION: The following references have been used in designa- ting strains of inbred mice and inbred rats, respectively: Staats, J. 1976. Standardized nomenclature for inbred strains of mice: Sixth listing. Cancer Res. 36:4333-4377. Festing, M., and J. Staats. 1973. Standardized nomenclature for inbred strains of rats. Fourth listing. Transplantation 16(3):221-245. 0 The strain designation is given in capital letters followed by a slash.

3 RODENTS · The substrain designation follows the slash and may be given as numbers or as individual or company codes. Numbers are used to denote substrains that were derived from a common strain but separated before the completion of inbreeding. The individual or company code, written as an initial capital letter followed by up to three lower case letters, indicates the name of the person, laboratory, or company holding the strain. Several codes may appear together, indicating the history of the strain when read from left to right. The current holder's code appears last (farthest right) in the line. · Abbreviations indicating rearing by means other than natural mother (listed previously) may be included. MICROBIOLOGICAL STATUS: Abbreviations have been listed previously. Ex- planations are provided in the "Terms and Definitions" section. PRESENT F NUMBER: Current generation of inbreeding, either since the animals were acquired by the current supplier, or over the entire history of the strain. SURGICAL MODIFICATIONS AVAILABLE: Surgical modifications of animals that can be provided by suppliers by arrangement. The abbreviations used have been listed previously. CODE: Code designations for suppliers. Names, addresses, and phone num- bers for suppliers are listed in the final section of the book. OTHER RODENTS Rodents other than those commonly used in the laboratory may be found in the section, "Other Vertebrates: Mammals."

4 RODENTS . . . MONGOLIAN (MON) GERBILS (Meriones unguiculatus) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code Anp:(MON) C __ Anp Chi:(MON) C 64 Chi Haf:(MON) C 67 Haf Has:(MON) C 76 cas, ova, others Has Hul:(MON) C __ Hul Rbc: BROWN BEAUTY(MON) C Rbc Tum:(MON) C 54 Tum Wbs:(MON)[linebred] C 71 Wbs

5 RODENTS MONGOLIAN (MON) GERBILS (Meriones unguiculatus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code MON/Has MON/Tum 32 MONGOLIAN (MON) GERBILS (Meriones unguiculatus) Mutant cas, ova, others Has Tum Microbio- Stock or Surgical Mutant logical Strain On Which Modifications Designation Status It Is Carried Available Code black spot Has:(MON) MON/Has Tum:(MON) Haf:(MON) cas, ova, others Has cas, ova, others Has Tum Haf

6 RODENTS GU INEA P IGS (cavia porcel l us3 Outbred Microbio- Colony Surgical Stock logical Closed Modifications Desi~nation Status 19-- Available Code DUNKIN-HARTLEY ( DH ) Bil:(DH) C 72 cas, ova Bil Cam:(DH) C 61 cas, ova Cam Dla:(DH)f' BR 75 ova Dla HARTLEY (HA) Anp:(HA) C __ Anp Cam:FCRC(HA) C 62 cas, ova Cam Cam:(HA) C 64 cas, ova Cam Cam: NON-RESPONDERS C 68 cas, ova Cam TO PLL(HA) Cam: RESPONDERS TO C 68 cas, ova Cam PLL(HA) Can:(HA) BR 69 Can Clc:(HA) C __ Clc Crc:(HA) C 62 Crc Crl:COBS@(HA) BR, DF 70 Crl Dsk:(HA) C __ Dsk Elm:(HA) C 69 adr, hyp, ova, Elm thy Fab:(HA)'' C __ cas, ova, others Fab Gin:(HA) C __ Gin COBS~ is a registered trademark of The Charles River Breeding Labor- atories, Inc., Wilmington, Massachusetts. Timed and untimed pregnant females available.

7 RODENTS GUINEA PIGS (Cavia porcellus) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code HARTLEY (HA) - cont. Mcr:(HA) New:(HA) Old:(HA) Pep:(HA) Roc:(HA) Sim:(HA) Suo:tHA) Swf:(HA) Wbs:(HA)[linebred] SHORTHAIR (SR) Akl:AK(SR) Anp:C(SR) Hla:(HA) BR 68 Hla Ils:(HA) C 65 Ils Kel:(HA) C 74 Kel C C C C C C C C C C C C Cam:MOEN CHASE A(SR) SHORTHAIR (SR)--AMERICAN Chr:AME RICAN C(SR) C Dsk:AMERICAN A(SR) Hul:AMERICAN A(SR) Hul:AMERICAN C(SR) Mcr 76 71 76 71 60 cas, ova New Old Pep Roc Sim Suo Swf Wbs Akl Anp Cam Chr Dsk Hul Hul

8 RODENTS GUINEA PIGS (Cavia porcell us) Outbred - Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code SHORTHAIR (SR)--AMERICAN - cont. Isa:AMERICAN AtSR) C Isa Isa:AMERICAN C(SR) C __ Isa Pad: AMERICAN C( SR) C __ Pad Ssi:AMERICAN A(SR) C 68 Ssi SHORTHAIR (SR)--ENGLISH Cam: ENGLISH A(SR) C __ cas, ova Cam Cam:ENGLISH C(SR) C -- . cas, ova Cam Dmf: ENGLISH A(SR) C 72 . Dmf Hla:ENGLISH A(SR) C __ Hla Hla:ENGLISH C(SR) C __ Hla Ils:ENGLISH A(SR) C 65 Ils C Ssi:ENGLISH A(SR) Ssi:ENGLISH C(SR) Thr: ENGLISH A(SR) Thr:ENGLISH C(SR) OTHER STOCKS Hul:ABYSSINIAN C Hul:PERWIAN C non-designated C 68 68 Ssi Ssi Thr Thr Hul Hul Drb non-designated C 58 Thr [1inebred-various colors]

9 RODENTS GUINEA PIGS (Cavia porcellus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code WRIGHT STRAIN 2 COBS~2/Crl BR -- Crl 2/Crc C 9 Crc 2/Elm§ C -- adr, hyp, ova, Elm thy WRIGHT STRAIN 13 COBS@13/Crl BR -- Crl 13/Crc C 51 Crc COBRA is a registered trademark of The Charles River Breeding Labor- atories, Inc., Wilmington, Massachusetts. §These guinea pigs now are being outbred, but in 1978 were found to be histocompatible with inbred Strain 2 animals from a number of other sources. GUINEA PIGS (Cavia porce77 us) Partially Inbred Microbio- Number of Stock logical Generations Designation Status of Inbreeding Code Emr:(HA) Emr

10 RODENTS HAMSTERS Outbred Microbio- Colony Stock logical Closed Designation Status 19-- Comments Code - ARMENIAN OR GREY (ARM) Iebs:(ARM) (Cricetulus migratorius ) C 64 CHINESE OR STRIPED-BACK (CHN) (Cricetulus griseus) prone to autoimmune diseases; free of spontaneous neoplasms; highly sensitive to low doses of chemical car- cinogens; life span 1000 days Iebs Chi:(CHN) C 64 Chi Iebs:(CHN) ~ 67 SYRIAN GOLDEN (SYR) (Mesocricetus auratus) low incidence of span- Iebs taneous neoplasms; model for adjuvant- induced lymphomatoid & sarcomatoid granulo- matosis, sarcoidosis, vasculitis, pancrea- titis, & insulitis; life span 1000 days Anp:(SYR) C __ Anp Bbh:(SYR) [albino] C 77 Bbh Bbh:(SYR) [various C 77 Bbh colors] Chi:(SYR) C 59 Chi Eng:ELA(SYR) BR 68 Eng Haf:(SYR) C 69 Haf Haf:(SYR) [albino] C 65 Haf Haf:(SYR) [black] C 75 Haf

11 RODENTS HAMSTERS Outbred Microbio-. Colony Stock logical Closed Designation Status 19-- Comments Code SYRIAN GOLDEN ~ SYR) (Mesocricetus auratus) - cont. Lak:LVG(SYR) C 51 surgical modifications: Lak adr, cas, hyp, ova, thy Mcr:(SYR) C __ Mcr Roc:(SYR) C __ Roc Sas:(SYR) C 73 Sas Sch:(SYR) BR 71 Sch Sim:(SYR) C 76 Sim Ssi:(SYR)f [outbred C and linebred] __ Ssi

12 RODENTS HAMSTERS Inbred Strain Microbio- logical Present Designation Status F Number Comments Code ARMENIAN OR GREY (ARM) (Cricetulus migratorius IV/Gy C 28 prone to age-related Iebs autoimmune diseases; life span 1000 days VIII/Gy C 31 prone to age-related Iebs autoimmune diseases; life span 1000 days CHINESE OR STRIPED-BACK (CHN) (Cricetulus griseus) A/Gy B/Gy Iebs 40 diabetes mellitus, Iebs uterine adenocar- cinoma; life span 1000 days 2A/bGy C 27 Iebs 8A/aGy C 25 Iebs SYRIAN GOLDEN (SYR) (Mesocricetus auratus) BIO~IPI/Bio § C 40 Bio BIO~PD4/Bio § C 75 Bio BIO~X.3/Bio § C 54 Bio BIO~X.68/Bio § C 51 Bio BIO~X.XB/Bio § C 52 Bio BIO~1.26/Bio § C 62 Bio BIO~ is a registered trademark of Bio-Research Consultants, Inc., Cambridge, Massachusetts. §Small numbers of surplus animals only may be available free of charge.

13 RODENTS HAMSTERS I nbred Microbio- Strain logical Present Designation Status F Number Comments Code SYRIAN GOLDEN (SYR) (Mesocricet7us auratus3 - cont. BIO@1.5/Bio § C 46 dental caries Bio BIO~2.4/Bio § C 52 benign prostatic Bio hyperplasia BIO@4.22/Bio § C 66 Bio BIO~4.24/Bio § C 58 congenital obesity; Bio high incidence of adrenal tumors BIO@7.88/Bio § C 57 Bio BIO@10.37/Bio § C 25 Bio BIO~11.10/Bio § C 36 BIO~15.16/Bio* C 46 Bio highly susceptible to methylcholanthrene- induced tumors (in- cidence higher in males than in females) and carcinogenic hydrocarbons; low incidence of spon- taneous tumors Bio BIO@41.56/Bio § C 39 congenital hetero- Bio chromia iridis BIO~45.5/Bio § C 39 Bio BIO~54.7/Bio § C 47 highly susceptible to Bio mammary tumor devel- opment in response to methylcholanthrene feeding *___Q BIONIC is a registered trademark of Bio-Research Consultants, Inc., Cambridge, Massachusetts. §Small numbers of surplus animals only may be available free of charge.

14 RODENTS HAMSTERS Inbred Strain Designation Microbio- logical Present Status F Number Comments Code SYRIAN GOLDEN (SYR) (Mesocricetus auratus) - cont. BIO(~)82. 73/Bio § BI 0(~)84 . 9/Bio § BIO(~)86. 93/Bio § BIO(~)87 . 20/Bio* C C C 45 41 35 46 CB/SsLak C 60 LHC/Lak C 54 LSH/SsLak C 62 §Small numbers of surplus animals only may be available free of charge. frequency of spontaneous mammary tumors low; frequency of methyl- cholanthrene-induced tumors high displays seizure-like activity, apparently heritable Bio Bio Bio congenital benign pro- Bio static hyperplasia; frequency of methylcho- lanthrene-induced mam- mary tumors high; significant incidence of methylcholanthrene- induced stomach tumors in males; frequency of methylcho- lanthrene-induced intes- tinal tumors higher in males than in females surgical modifications: adr, cas, hyp, ova, thy surgical modifications: adr, cas, hyp, ova, thy surgical modifications: adr, cas, hyp, ova, thy *BIO~ is a registered trademark of Bio-Research Consultants, Inc., Cambridge, Massachusetts. Lak Lak Lak

15 RODENTS HAMSTERS Inbred Strain Designation Microbio- logical Status Present F Number Comments SYRIAN GOLDEN (SYR) (Mesocricetus auratus) - Cont. MHA/SsLak C 52 PD4/Lak C 47 Code surgical modifications: adr, cas, hyp, ova, thy surgical modifications adr, cas, hyp, ova, thy Lak : Lak

16 RODENTS HAMSTERS Hybrid Microbio- Hybrid logical Designation Status Parental Strains Code ARMENIAN OR GREY (ARM) (Cri cetul us migra tori us ) VIII x IV C VIII/Gy x IV/Gy Iebs CHINESE OR STRIPED-BACK (CHN) (Cricetulus griseus) A x B C A/Gy x B/Gy Iebs SYRIAN GOLDEN (SYR) (Mesocricetus auratus) BIO(~F1B BIO@F1D C C BIO~87.20/Bio x BIO~1.5/Bio* Bio BIO~87.20/Bio x BIO~15.6/Bio* Bio F1 hybrids of any inbred BIONIC strains are available upon request, but are not maintained routinely *RIOT is a registered trademark of Bio-Research Consultants, Inc. Cambridge, Massachusetts.

17 RODENTS HAMSTERS Mutant Mutant Designation Microbio- logical Strain(s) on Which Status It Is Carried Code CHINESE OR STRIPED-BACK (CHN) (Cricetulus migratorius) bb ( Brittle- bristle, maturity onset hair follicle ab- normality in females partial alopecia) - C SYRIAN GOLDEN (SYR) (Mesocricetus auratus) cm (Cardiomyopathy) by (Hydrocephalus) pa ( Hind-leg paralysis) sz (Seizure) WE (Anophthalmia) C A/Gy BIO~ 4.6/Bio BI0~40.54/Bio*§ BI0~53.58/Bio BI0~82.62/Bio § BI0~35.97/Bio § BI0~12.14/Bio § BI0~86.93/Bio § BI0~72.29/Bio § BIONIC is a registered trademark of Bio-Research Consultants, Inc., Cambridge, Massachusetts. tSmall numbers of surplus animals only may be available free of charge. Iebs Bio Bio Bio Bio Bio

18 RODENTS MICE (Mus musculus) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code CF1~* Can: COBS@CF1@ BR 75 adr, cas, hyp, Can ova, thy Crl:COBS~CF1~ BR, DF, 35 adr, cas, hyp, Crl GF ova, thy Mcr:CF1~ C -- Mcr Sas:CF1@ C 78 & 79 Sas (two colonies) Sch:CF1~ BR, 73 Sch GF, GN HAUSCHKA INSTITUTE FOR CANCER RESEARCH HA(ICR) Blu:HA(ICR) BR 58 adr, cas, hyp, Blu ova Cam:HA(ICR) C 65 adr, cas, ova Cam Cum:HA(ICR) BR 60 Cum Spb:HA(ICR) C 68 Spb INSTITUTE FOR CANCER RESEARCH (ICR) Cam:(ICR) C 65 Cam Can:COBS~CD~-1(ICR) BR 70 adr, cas, hyp, Can ova, thy Crl:CD@-1(ICR) BR, DF, 59 adr, cas, hyp, Crl GF ova, thy Dub:(ICR) C 58 adr, cas, ova, Dub pan, thy COBS@, CD@, and CF1~ are registered trademarks of The Charles River Breeding Laboratories, Inc., Wilmington, Massachusetts.

RODENTS MICE (Mus musculus) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code . INSTITUTE FOR CANCER RESEARCH ( ICR) - cont . Fln:FRF-2(ICR) C 60 Fln Haf:(ICR) C 70 Haf Hap:(ICR)f BR, DF, 65 adr, cas, hyp, Hap GF, GN nep, ova, thy Hla:(ICR) BR 67 Hla Lai:COX(ICR) BR, DF, 60 Lai GF Pep:(ICR) C 67 Pep Roc:(ICR) C __ Roc Roy:(ICR) C 53 Roy Saf:(ICR) BR 61 Saf Sch:(ICR) BR, 56 Sch GF, GN Sim:(ICR)f BR 72 Sim Tex:(ICR)f BR, DF, G9 Tex GF, GN SWISS (S) Hap:ND/4(S)f BR, DF, 72 adr, cas, hyp, Hap GF, GN nep, ova, thy Lai:COX NIH(S) BR, DF, 75 Lai GF Mai:NIH(S) BR 68 Mai Roc:(S) C __ Roc

20 RODENTS MICE (Mus musculus) Outbred M'crobio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code SWI SS WEBSTER ( SW ) Anp:(SW) C __ Anp Bil:(SW) C 60 cas, ova Bil Cam:(SW) C 65 Cam Crl:COBS~CFW~(SW) BR, DF, 37 adr, cas, hyp, Crl GF ova, thy Hla:(SW) BR 67 Hla Lai:COX(SW) BR, DF, 50 Lai GF Mcr:COX(SW) C __ Mcr Roc:(SW) C __ Roc Sim:(SW)f BR 56 Sim Suo:(SW) C 56 Suo Sut:(SW) C 37 Sut Tac:(SW)f BR 40 adr, cas, hyp, Tac ova, pan, pare, tier, thy, others OTHER STOCKS Akl:AK C 62 Akl Lai:COX(STANDARD) BR, DF, 37 Lai GF COBS~ and CFW~ are registered trademarks of The Charles River Breeding Laboratories, Inc., Wilmington, Massachusetts.

21 RODENTS MICE (Mus musculus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code A/HeCum BR Cum A/HeJ BR 176 3ax A/J BR 172 Jax A/WySn BR 164 Jax AKR/Cum BR Cum AKR/J BR 136 Jax AKR/Jfh[J74] BR 136 Jax AU/SsJ BR 41 Jax BALB/cAnCrMaif BR 34 Mai BALB/cAnHapf BR, DF, 4 Hap GN BALB/cAnNCrl BR, DF, 6 adr, cas, hyp, Crl GF ova, thy BALB/cAnNSaf BR 9 Saf BALB/cAnSimf BR 39 Sim BALB/cAnTexf BR, DF, 5-10 GF, GN Tex BALB/cByJ BR 145 Jax BALB/cCox BR, DF, 144 Lai GF BALB/cCum BALB/cDub BR C Cum 56 adr, cas, ova, Dub pan, thy BALB/cJ BR 128 Jax BDP/J BR 101 Jax BUB/BnJ BR 101 Jax

22 RODENTS _ 11ICE (Mus musculus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code CBA/CaJ BR 93 Jax CBA/Cum BR Cum CBA/H-T6J BR 65 Jax CBA/J BR 172 Jax CE/J BR 78 Jax C3H/AnCumf BR Cum C3H/BiMaif BR 42 Mai C3H/BiSim C 49 Sim C3H/HeCox BR, DF, 135 Lai GF C3H/HeDub C 45 adr, cas, ova, Dub pan, thy C3H/HeHapf BR, DF, 4 adr, cas, hyp, Hap GF, GN nep, ova, thy C3H/HeJ BR 156 Jax C3H/HeJfh[J67] BR 142 Jax C3H/HeNCrl BR, DF, 10 adr, cas, hyp, Crl GF ova, thy C3H/HeSch GF, GN 33 Sch C3H/HeSn BR 94 Jax C3H/HeTex f C3H/NCrlCan BR, DF, 3-10 GF, GN BR Tex Can C3HeB/FeJ BR 101 Jax C57BL/Cum BR Cum C57BL/KsJ BR 44 Jax

23 RODENTS MICE (Mus musculus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code C57BL/6By BR 108 Jax C57BL/6Cox BR, DF, 130 Lai GF C57BL/6Cum BR Cum C57BL/6Hapf BR, DF, 5 adr, cas, hyp, Hap GF, GN nep, ova, thy C57BL/6J BR 128 Jax C57BL/6Jfh[J67] BR 123 Jax C57BL/6Maif BR 38 Mai C57BL/6NCrl BR, DF, 5 adr, cas, hyp, Crl GF ova, thy C57BL/6NCrlCan BR adr, cas, hyp, Can ova, thy C57BL/6NSaf BR 9 Saf C57BL/6Sch BR, 21 Sch GF, GN C57BL/6Sim C 25 Sim C57BL/6Texf BR, DF, GF, GN 2-12 Tex C57BL/10J BR 135 Jax C57BL/10Sn BR 113 Jax C57BR/cdJ BR 162 Jax C57L/J BR 139 Jax C58/J BR 175 Jax DBA/1J BR 96 Jax DBA/2Cox BR, DF, 130 Lai GF

24 RODENTS MICE (Mus musculus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code DBA/2Cum BR Cum DBA/2DeJ BR 116 Jax DBA/2Hapf BR, DF, 3 Hap GN DBA/2J BR 127 Jax DBA/2Jfh[J67] BR 126 Jax DBA/2Maif BR 41 Mai DBA/2NCrl BR, DF, 6 adr, cas, hyp, Crl GF ova, thy DBA/2NSaf BR 7 Saf DBA/2CrSch BR, 17 Sch GF, GN DBA/2Sim C 30 Sim DBA/2Texf BR, DF, 3-10 Tex GF, GN DDS/Cox BR, DF, 85 Lai GF I/LnJ BR 61 Jax LG/J BR 75 Jax LP/J BR 103 Jax MA/MyJ BR 106 Jax NZB/B1NJ BR 99 Jax P/J BR 132 Jax PL/J BR 108 Jax RF/J BR 89 Jax

25 RODENTS MICE (Mus musculus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code RIIIS/J [formerly BR 36 Jax RIII/2J] SEA/GnJ BR 121 Jax SEC/I ReJ BR 119 Jax SJL/J BR 82 Jax SM/J BR 88 Jax ST/bJ BR 122 Jax SWR/J BR 126 Jax 129/J BR 78 Jax 129/Sv BR 35 Jax

26 RODENTS MICE (Mus musculus) Congenic Resistant Strains Microbio- Strain logical Present Designation Status F Number Code A.By/Sn BR 26 Jax A.SW/Sn BR 23 Jax B6.c_H_2ba/By BR 38 Jax B10.A/SgSn BR 43 Jax B10.A(2R)/SgSn BR 41 Jax B10.A(5R)/SgSn BR 35 Jax B10.AKM/Sn BR 30 Jax B10.BR/SgSn BR 40 Jax B10.D2/nSn BR 55 Jax B10.D2/oSn BR 73 Jax C3H-H-2O/SfSn BR 26 Jax C3H.SW/Sn BR 20 Jax

27 RODENTS MI CE (Mus musculus ) Hybri d Hybrid Microbio- Surgical Desig- logical Modifications nation Status Parental Strains Available Code AKD2F1 BR AKR/J x DBA/2J Jax BC3F1 BR C57BL/Cum x C3H/AnCumf Cum B6AF1 BR C57BL/6J x A/J Jax B6CBF1 BR C57BL/6Cum x CBA/Cum Cum B6C3F' BR, DF C57BL/6NCrl x C3H/HeNCrl Crl B6C3F1 BR C57BL/6Cum x C3H/AnCumf Cum B6C3F1 BR C57BL/6Hap x C3H/HeHap adr, cas, hyp, Hap nep, ova, thy B6D2F1 BR C57BL/6Cum x DBA/2Cum Cum B6D2F1 BR C57BL/6J x DBA/2J Jax B6D2F1 BR, DF, C57BL/6Cox x DBA/2Cox Lai GF B6D2F1 BR C57BL/6NSaf x DBA/2NSaf Saf B6D2F' BR, GF C57BL/6Sch x DBA/2CrSch Sch B6D2F~ C C57BL/6Sim x DBA/2Sim Sim B6D2F1f BR, DF, C57BL/6Tex x DBA/2Tex Tex GN CAF1 BR BALB/cCum x A/HeCum Cum CAF1 BR BALB/cJ x A/J Jax CB6F1 BR BALB/cJ x C57BL/6J Jax CD2F1 BR BALB/cCum x DBA/2Cum Cum CD2F1 BR BALB/cAnHap x DBA/2Hap adr, cas, hyp, Hap nep, ova, thy CD2F CD2F BR, DF, BALB/cCox x DBA/2Cox GF BR BALB/cAnNSaf x DBA/2NSaf Lai Saf

28 RODENTS MICE bus musculus) Hybrid Hybrid Microbio- Surgical Desig- logical Modifications nation Status Parental Strains Available Code C3BF1 BR C3H/AnCumf x C57BL/Cum Cum C3D2F1 BR C3H/HeJ x DBA/2J Jax LAF1 BR C57L/J x A,/HeJ Jax

29 RODENTS MICE (~us musculus) Mutant Microbio- Stock or Strain Mutant logical On Which It is Designation Status Carried Code AY (Yellow) BR C57BL/6J-AY/a Jax b~ (Beige) BR C57BL/6J-bi Jax c2J (Albino-2J) BR C57BL/6J-c2J Jax db (Diabetes--Closely BR C57BL/KsJ-db +/+ m Jax linked [in repul- sion] with Misty, m, a coat color gene) dw (Dwarf) BR DW/J-dw Jax d y ( Dystrophia BR C57BL/6J- d y Jax muscularis) BR 129/ReJ-dy Jax BR 129B6F1/J-dg Jax dy23 (Dystrophia BR C57BL/6J-dy27 Jax muscularis-2J) hr (Hairless) BR HRS/J-hr Jax nu (Nude) BR, DF, Hap:NIH(S)-nuf Hap GF, GN BR, DF, Lai:COX NIH(S)-nu Lai GF GF, GN Sch:(BALB/cAnBom)-nu Sch GN Tac:NIH(S)-nu Tac ob ( Obese) C C57BL/6J- ob Fab BR C57BL/6J- ob Jax S1 ( Steel) BR WC/Re-Sl/+ Jax Sld ( Steel-Dickie) BR C57BL/6J-Sld/+ Jax W (Dominant spotting) BR WB/ReJ-W/+ Jax wv (Viable dominant BR C57BL/6J-WV/+ Jax spotting)

30 RODENTS RATS (Rattus norvegicus ) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code BUFFALO ( BUF ) Mlr:(BUF) BR -- HOLTZMAN SPRAGUE-DAWLEY~) H ( SD ) * Crl:COES~CD@H(SD) BR, DF, GF Mlr 75 adr, cas, hyp, Crl ova, thy Hot:H(SD) C __ Hot Sas:H(SD) C 66 Sas LONG EVANS ( LE ) Blu:(LE) BR 64 adr, cas, hyp, Blu ova, thr Can:COBS@(LE) BR 71 adr, cas, hyp, Can ova, thy Haf:(LE) C 70 Haf Mar:MFL(LE) BR 63 adr, cas, hyp, Mar ova, thy, Grollman modification Mlr:(LE) BR -- cas Mlr Pep:(LE) C 65 Pep Roc:(LE) C __ Roc Sim:(LE) BR 49 adr, cas, hyp, Sim ova, pan, thy * Sprague-Dawley~ is a registered trademark of The Mogul Corporation, Chagrin Falls, Ohio. COBS~ and CD~ are registered trademarks of The Charles River Breeding Laboratories, Inc., Wilmington, Massachusetts.

31 RODENTS RATS (Rattus norvegicus ) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code MUNICH WISTAR MUN(WI) Tex:MUN(WI)~ BR, DF 76 GF, GN OSBORNE MENDEL (OM) Tex Cam: (OM) C 53 adr, cas, hyp, Cam ova, pan, thy, parabiosis Roc: (OM) C __ Roc SHERMAN (SH) BTU: (SH) BR 73 adr, cas, hyp, Blu ova, thr Cam: (SH) C 53 adr, cas, hyp, Cam ova, pan, thy, parabiosis Roc: (SH) C __ Roc SPONTANEOUSLY HYPERTENSIVE (SHR) Tac:N(SHR)f BR -- adr, cas, hyp, Tac ova, pan, thy, others SPRAGUE-DAWLEY(~(SD)* Anp:(SD) C __ Anp Bil: (SD) C 67 cas, ova Bil Sprague-Dawley~ is a registered trademark of The Mogul Corporation, Chagrin Falls, Ohio.

32 RODENTS RATS (Rattus norvegicus) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code S P RAGU E - DAWL KY(~) ~ SD ~ * - con ~t. Blu:(SD) BR 54 adr, cas, hyp, Blu ova, thr Cam:(SD)f BR, DF 76 adr, cas, hyp, Cam GF, GN ova, pan, thy, parabiosis Can: COBS~CD@(SD) BR 70 adr, cas, hyp, Can ova, thy Crl:COBS~CD~(SD) BR, DF, 50 adr, cas, hyp, Crl GF ova, thy Dub:(SD) C 70 adr, cas, ova, Dub pan, thy Fab:(SD)'' C __ adr, cas, ova Fab Haf:(SD) C 67 Haf Hap:(SD)f BR, DF, 75 adr, cas, hyp, Hap GF, GN nep, ova, pare, tier, thy Hla:(SD) BR 72 Hla Kng:(SD) BR 77 Kng Lai:COX(SD) BR, DF, 67 Lai GF Mac:ML(SD)§ C 58 Mac * Sprague-Dawley~ is a registered trademark of The Mogul Corporation, Chagrin Falls, Ohio. COBS~ and CD~ are registered trademarks of The Charles River Breeding Laboratories, Inc., Wilmington, Massachusetts. 11 Timed and untimed pregnant females available. § Mackesey Laboratories (Mac) accepts standing orders only.

RODENTS RATS (Rattus norvegicus ) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code SPRAGUE-DAWLEY(~) (SD )* - cont. Mar:MFS(SD)1l BR 77 adr, cas, hyp, Mar ova, thy, Grollman modification Mcr:(SD) C __ Mcr Pep:(SD) C 65 Pep Roc:(SD) C __ Roc Saf:(SD) BR 66 Saf Sas:(SD) DF 79 Sas Sch: SPRAGUE- BR, GF 29 Sch DAWLEY~(SD) Sim:(SD)f BR, DF, 58 adr, cas, hyp, Sim GN ova, pan, thy Spb:(SD) C 63 cas, ova, thy Spb Suo:(SD) C S4 Suo Tac:N(SD)f BR -- adr, cas, hyp, Tac ova, pan, thy, others Tex:(SD)f BR, DF, 69 Tex GF, GN Zml:ZM(SD)f§ BR 67 adr, cas, hyp, Zml ova, pan, thy, others Sprague-Dawley~ is a registered trademark of The Mogul Corporation, Chagrin Falls, Ohio. . . Timed and untimed pregnant females available. Arrangements can be made for animals to be held up to 24 months of age. §Timed pregnant females and animals over 18 months of age available.

34 RODENTS RATS (Rattus norvegicus) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code ~ _ l~lISTAR (hlI ) Anp:(WI) C __ Anp Cam:(WI) C 64 adr, cas, hyp, Cam ova, pan, thy, parabiosis Can:COBS~(WI) BR 74 adr, cas, hyp, Can ova, pan, thy Crl:COBS@(WI) BR, DF, 75 adr, cas, hyp, Crl GF ova, thy Fab:(WI)'' C __ adr, cas, ova Fab Hap:(WI)f BR, DF, 46 adr, cas, hyp, Hap GF, GN nep, ova, pare, tier, thy Hla:(WI) BR 56 Hla Lai:COX(WI) BR, DF, 69 Lai GF Mar:MFW(WI) 11§ BR 72 adr, cas, hyp, Mar ova, thy, Grollman modification Pep:(WI) Roc:(WI) Roy:(WI) 69 Pep Roc Roy Sim:(WI) BR 57 adr, cas, hyp, Sim ova, pan, thy ** fii' COBSV is a registered trademark of The Charles River Breeding Labora- tories, Inc., Wilmington, Massachusetts. ~1 Timed and untimed pregnant females available. § Arrangements can be made for animals to be held up to 24 months of age.

35 RODENTS RATS (Rattus norvegic7~s) Outbred Microbio- Colony Surgical Stock logical Closed Modifications Designation Status 19-- Available Code hlISTAR (WI ) - cont. Wbs:(WI) [linebred] C 74 Wbs WISTAR KYOTO (Lilly ) @ Tac:N(WKY)f BR -- adr, cas, hyp, ova, pan, thy, others @Control animals for Spontaneously Hypertensive (SHR) rats.

Strain 36 RODENTS RATS (,Rattu5 norvegicusj Partially Inbred Microbio- Number of Surgical Modifications logical Generations Designation Status of Inbreeding Available Code LONG EVANS ( LE ) Mlr:(LE) BR 8 cas Mlr SPRAGUE-DAhlLEY(g) (SD) Mlr:(SD) BR 8 cas Mlr Sprague-Dawley~ is a registered trademark of The Mogul Corporation, Chagrin Falls, Ohio.

37 RODENTS RATS (Rattus norvegicus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code ACI ACI/Sim BRO1~IN NORWAY ( BN ) c ACI/Cox BR, DF, 100 Lai GF ACI/Hapf BR, DF, 5 adr, cas, hyp, Hap GN nep, ova, pare, tier, thy ACI/Maif BR 98 Mai 32 adr, cas, hyp, Sim ova, pan, thy BN/Maif BR 41 Mai BUFFALO ( BUF ) BUF/Cox BR, DF, 96 Lai GF BUF/Maif BR 76 Mai BUF/Sim 47 adr, cas, hyp, Sim ova, pan, thy BUF/Texf BR, DF, 10-15 Tex GF, GN FISCHER 344 (F344) COBS~CDF@F344/Crl BR, DF, 22 adr, cas, hyp, Crl GF ova, thy COBS~ and CDF~ are registered trademarks of The Charles River Breed- ing Laboratories, Inc., Wilmington, Massachusetts.

38 RODENTS RATS (Rattus norvegicus) Inbred Microbio- Surgical Strain logical Present Modifications Desiqnation Status F Number Available Code FISCHER 344 (F344) - cont. F344/Cox BR, DF, 128 Lai GF F344/Hapf BR, DF, 3 adr, cas, hyp, Hap GF, GN nep, ova, pare, tier, thy F344/Maif BR 112 Mai F344/Sch BR, 26 Sch GF, GN F344/Simf BR 41 adr, cas, hyp, Sim ova, pan, thy GENETICALLY HYPERTENSIVE (GH) GH/Zml BR 20+ adr, cas, hyp, ~ml ova, pan, thy, others LEWIS (LEW) COBS~LEW/Crl BR, DF, 52 adr, cas, hyp, Crl GF ova, thy LEW/Maif BR 79 Mai MAXX MAXX/Maif BR 28 Mai COB S~ is a registered trademark of The Charles River Breeding Labora- tories, Inc., Wilmington, Massachusetts.

39 RODENTS RATS (Rattus norvegicus) Inbred Microbio- Surgical Strain logical Present Modifications Designation Status F Number Available Code SPONTANEOUSLY HYPERTENSIVE (SHR) COBS@SHR/NCrl BR, DF, adr, cas, hyp, Crl GF ova, thy SHR/Cox BR, DF 41 Lai GF SPRAGUE-DAWLEY~ (SD) MLSI(SD)/Mac§ C 80 Mac WISTAR FURTH (WF) WF/Maif BR 62 Mai WF/Schf BR, 29 Sch GF, GN WISTAR KYOTO (WKY)@ COBS ~ Y/NCrl BR, DF, adr, cas, hyp, Crl GF ova, thy WKY/Cox BR, DF, 15 Lai GF Sprague-Dawley~ is a registered trademark of The Mogul Corporation, Chagrin Falls, Ohio. COB S~ is a registered trademark of The Charles River Breeding Labora- tories, Inc., Wilmington, Massachusetts. § Mackesey Laboratories (Mac) accepts standing orders only . @ Control an~mals for Spontaneously Hypertensive (SHR) rats.

40 RODENTS RATS (Rattus norvegicus ) Hybri d Hybrid Microbiological Designation Status Parental Strains Code LBNF1 BR LEW/Mai x BN/Mai Mai RATS (Rattus norvegicus ) Mutant Microbio- &rgical logical Modifications Mutant Designation Status Available Code j (Jaundice or Gunn) BR fa (Fatty or Zucker) C di (Diabetes insipidus BR or Brattleboro) GH (Genetically See inbred rat listing. hypertensive) SHR (Spontaneously hypertensive) adr, cas, hyp, Blu ova, thr adr, cas, hyp, Fab pan, thy adr, cas, hyp, Blu ova See inbred and outbred rat listings.

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