Chemical Safety and |
A Guide to Developing
Standard Operating Procedures
Committee on Chemical Management Toolkit Expansion: Standard Operating Procedures
Board on Chemical Sciences and Technology
Division on Earth and Life Studies
THE NATIONAL ACADEMIES PRESS
Washington, DC
THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001 This activity was supported by Contract/Grant No. S-ISNCT-14-CA-1013 between the National Academy of Sciences and the Department of State. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. International Standard Book Number-13: 978-0-309-39220-4 Additional copies of this report are available for sale from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu. Copyright 2016 by the National Academy of Sciences. Suggested citation: National Academies of Sciences, Engineering, and Medicine. (2016). Chemical Laboratory Safety and Security: A Guide to Developing Standard Operating Procedures. Committee on Chemical Management Toolkit Expansion: Standard Operating Procedures. Washington, DC: The National Academies Press. doi: 10.17226/21918.
International Standard Book Number-10: 0-309-39220-9
Digital Object Identifier: 10.17226/21918
All rights reserved.
Printed in the United States of America
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Learn more about the National Academies of Sciences, Engineering, and Medicine at www.national-academies.org.
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COMMITTEE ON CHEMICAL MANAGEMENT TOOLKIT EXPANSION: STANDARD OPERATING PROCEDURES
Members
NED D. HEINDEL (Chair), Lehigh University
MONTGOMERY ALGER, Pennsylvania State University
WILLIAM BULLOCK, Bristol-Myers Squibb
MARK C. CESA, INEOS USA LLC (Ret.)
THOMAS F. EDGAR, University of Texas, Austin
PATRICK J. LIM, University of San Carlos
KENNETH G. MOLOY, National Science Foundation
SUPAWAN TANTAYANON, Chulalongkorn University
Staff
CAMLY TRAN, Study Director (as of January 1, 2016)
KATHRYN HUGHES, Senior Program Officer (through January 1, 2016)
CLAIRE BALLWEG, Program Coordinator (as of January 1, 2016)
CARL-GUSTAV ANDERSON, Research Associate (through January 1, 2016)
COTILYA BROWN, Senior Program Assistant (through January 1, 2016)
BOARD ON CHEMICAL SCIENCES AND TECHNOLOGY
Members
DAVID BEM (Co-Chair), PPG Industries
DAVID WALT (Co-Chair), Tufts University
HÉCTOR D. ABRUÑA, Cornell University
JOEL C. BARRISH, Achillion Pharmaceuticals, Inc.
MARK A. BARTEAU, University of Michigan
JOAN BRENNECKE, University of Notre Dame
MICHELLE V. BUCHANAN, Oak Ridge National Laboratory
DAVID W. CHRISTIANSON, University of Pennsylvania
JENNIFER S. CURTIS, University of California, Davis
RICHARD EISENBERG, University of Rochester
SAMUEL H. GELLMAN, University of Wisconsin-Madison
SHARON C. GLOTZER, University of Michigan
MIRIAM E. JOHN, Sandia National Laboratories (Ret.)
FRANCES S. LIGLER, University of North Carolina, Chapel Hill and North Carolina State University
SANDER G. MILLS, Merck Research Laboratories (Ret.)
JOSEPH B. POWELL, Shell, Houston
PETER J. ROSSKY, Rice University
TIMOTHY SWAGER, Massachusetts Institute of Technology
Staff
TERESA FRYBERGER, Director
DOUGLAS FRIEDMAN, Senior Program Officer
CAMLY TRAN, Associate Program Officer
CLAIRE BALLWEG, Program Coordinator
ACKNOWLEDGMENT OF REVIEWERS
This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the process. We wish to thank the following individuals for their review of this report:
John Brauman, Stanford University
Muhammad Iqbal Choudary, University of Karachi
Kimberly Jeske, Oak Ridge National Laboratory
Royce Murray, University of North Carolina at Chapel Hill
Russell W. Phifer, WC Environmental, LLC
Lori Seiler, The Dow Chemical Company
Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the report’s conclusions or recommendations, nor did they see the final draft of the report before the release. The review of this report was overseen by Stephen Berry of the University of Chicago. He was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.
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The Guide to Developing Standard Operating Procedures is meant to be used with the Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management and the accompanying toolkit.
These materials are available on the Internet at www.dels.nas.edu/global/bcst/Chemical-Management.
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CONTENTS
1 STANDARD OPERATING PROCEDURES FOR CHEMICAL SAFETY
What Is a Standard Operating Procedure?
Who Is Responsible for Developing Standard Operating Procedures?
Guide to Developing Standard Operating Procedures
Assessment of Process Conditions
4 STANDARD OPERATING PROCEDURE FORMS
5 APPLICATION OF THE GUIDE TO DEVELOPING STANDARD OPERATING PROCEDURES
Scenario 1: Neutralization of Carbonate by Acid
Scenario 2: Use and Filtration of a Pyrophoric Catalyst
Scenario 3: Toxic and Explosive Gases: Handling Diazomethane and Alternatives
Moderate Risk Standard Operating Procedure Form