Summary tables of biological tests: Volume 7 No. 4 : August 1955 (1955)

Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

-539- T A B L E IV RODENT R E P E L L E N C Y TESTS Screening Agency: F i s h and W i l d l i f e Service, L a u r e l , M a r y l a n d Technique: Alb ino and hooded ra ts (150-350 gm. ) . Th i s test i s based on the ad l i b i t u m food acceptance of tre^ited (2% of the test chemical ) and untreated baits (20 gm. of each). Da i l y records f o r four days are used to compute the repel lency index. A value of 85 or higher denotes a candidate repel lent . CBC No. 404,562 (55) 400,346 (8) Name and Structure Ace t ic acid, ch lo ro - , diester w i t h 4 ,4 ' - thiodiphenol CICH2COO ^ OOCCH2CI Acet ic acid, ch lo ro - , pentachlorophenyl ester Repellency Index 90.0 87.9 OOCCH2CI 400,384 (29) (41) Acet ic acid, ( £ - c h l o r o p h e n y l ) - C l ^ ^ CH2COOH 501,529-66 Ace t ic acid, ( e thy lened in i t r i lo ) t e t ra - , (2) d isodium salt, dihydrate HOOCCH NaOOCCH NCH2CH2N H2COOH 501,529-75 Ace t ic acid, ( e thy lened in i t r i lo ) t e t r a - . (2) t r i s o d i u m salt , monohydrate NaOOCCH NaOOCCH CH2CH2N ^ ^ C H 2 C O O N a CH2COOH 34.0 •34.0 2 H2O •115.0 H2O

-540- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure Repellency Index 500,788 Acetic acid, phenyl-, 100.0 (55) 2-phenylhydrazide ^ ^ ^ N H N H C O C H ^ ^ 404,577 Acetic acid, (2,3,5,6-tetrachloro- 97.0 (8) phenoxy) - CI CI OCH^COOH CI CI 500,009 Acetoacetanilide 27.5 (29) / \NHCOCH2COCH3 403,749 Acetophenone, 2-(benzylthio)- 54.5 (69) ^COCH^SCH^*^ ^ 500,962 Acetophenone, 2- (£-d imethylamino- 74,1 (55) phenylimino)-2-phenyl- 501,058 Allantoin I6.O (29) H^NCONHj^ ^ = 0 0 = -N

-541- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure Repellency Index 500,613-Al Ammonium compound, ^jj^pzyl- 97.5 (44) d i m e t h y l ^ - [ 2 - ( £ - l , l , 3 , 3 - ^ t r a n i e t h y l - butylphenoxy)ethoxy]ethyi} - - thiocyanate (CH3)3CCH2C(CH3)2^^^^0CH2CH20CH2CH2l^(CH3)2CH^ ^ (23) SCN 501,448 Aniline, N-ethyl-2,4-dini tro- 96.9 (55) lO. 'ft 2 02N^̂ ^̂ J NHC2H5 402,209 Anisole, 2,4,5-tr ichloro- 81.0 (8) Cl 500,140 Benzaldehyde, p -n i t ro - 73.6 (29) ^ 2 ^ ^ ^ ^ CHO O . K / 501,008 Benzamide, N-butyl -p-ni t ro- 78.0 CONH(CH2)3CH3 501,007 Benzamide, N,N-diethyl-p-ni t ro- 90.5 (55) ^ 2 ^ ^ ^ CON(C2H5)2 501,034 Benzamide, N,N-diisopropyl-p-ni tro- 84.8 (55) ^ Z ^ { \ CON[CH(CH3)2]2

-542- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure Repellency Index 501,017 Benzamide, N-isopropyl-D-mtro- 86.5 (55) O ^ N / \ C O N H C H ( C H 3 ) 2 501,025 Benzamide, N-methyl-p-ni t ro- 92.0 (55) ^ 2 ^ \ /CONHCH3 501,035 Benzamide, p-ni t ro-N,N-dipropyl- 90.0 (55) 0 2 N / \ CON(CH2CH2CH3)2 501,016 Benzamide, p-n i t ro-N-propyl - 92.4 CONHCH2CH2CH3 403,200-65 Benzenesulfinic acid, £ - c h l o r o - , 89.2 (53) sodium salt C l f \) S02Na 404,040 Benzenesulfonic acid, th io l - , 70.9 (47) phenyl ester 400,073 Butyraldehyde, 2,2,3-tr ichloro- 40.3 (44) CH3CHCICCI2CHO 500,269 Carbanilic acid, ethyl ester 95,6 (29) (49) ^ ^NHCOOC2H5

•543- RODENT CBC No. 404.042 (8) REPELLENCY TESTS (Continued) Name and Structure Carbonic acid, mono(2,4,5~trichloro- phenyl) esteri diester with diethylene glycol 403.748 (68) 500.006 (53) 400.835 (55) 404,079 (68) Repellency Index -42.0 CI CI C l ^ ^ OC(;0)OCH3CH30CH^CH^OC(:0)0^^ ^ C I CI CI Chalcone, 4-chloro- 30.0 C K y C H = C H C o-Cresol, 4,6-dinitro-, acetate JO, ^ N 02N^^^ J OOCCH3 CH3 o-Cresol, 3,4,6-trichloro-a-(2,3.5- tr ichloro-6 -methoxyphenyl) - OH OCH3 C l f f ^ ^ C H p . ^ ^ ^ CI 2-Cyclohexen-l-one, 3-(m-chloro- phenyl) - " 97.1 42.4 63.4 402,656 2-Cyclohexen-l-one, 2,3,4,4,5,6,6- (55) heptachloro- 84.0

-544- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure Repellency Index 401,01-0 Ethane, 1,1,1-trichloro-2,2-bis- - 29.2 (55) (3,5 -dichloro -2 -methoxyphenyl) - CI QCH3 CH3O ^Cl CI ci Cl CC13 401,054 Ethanol, 2-(pentachlorophenoxy)- 94.2 (53) Cl Cl \ OCH2 CH2OH c r ^ i 404,548 Ether, butyl 2,3,5,6-tetrachlorophenyl 79.0 (8) 0(CH2)3CH c i , r ^ c i ^ ^ Cl 501,462 Glycinonitri le, N-(o-methoxyphenyl)- 99.6 (55) '3 IHCH2CN 501,250 Glycolur i l 26.9 (44) . N ^ ^ N , N 1 N 403,638 Hexanedioic acid, octafluoro- -10.0 (35) HOOCCF2CF2CF2CF2COOH 501,377 Hydrazine, 1,2-dibenzoyl- 93.9 (55) ^ ^ ^ ^ C O N H N H C O ^ J

•545- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure 400,718 (29) 400.013 (47) Isethionic acid HOCH2CH2SO3H Ketone, methyl 2-thienyl S. Of OCH, Repellency Index -19.0 88.8 404.039 (25) 501,076 (53) 403,757 (14) 4,7-Methanoindene-l ,8-dione, 2,3.3a,4,5,6,7,7a-octachloro- 3a.4.7.7a-^etrahydro- 63.6 J^l C l c=o CI Cl 4-Morpholineethanol ICH2CH2OH 2-Naphthol, 1.6-dibromo- 49.4 91.4 403.637 (35) Oxepane. dodecafluoro- F ,C ' 1 F2C- CF- CF. - t F , -46.5

•546- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure 403,639 (35) 404,547 (9) 404,487 (8) Oxonane, hexadecafluoro- '0> CF- -CF. F2C- Phenol, 2(and 4)-(2-butenyl)- 4(and 2),6-dichloro- OH CI and Repellency Index -119.0 OH CH2CH=CHCH3 CI Phenol, x-butyl-x,x,x,x-tetrachloro- OH 80.0 CH2CH=CHCH3 97.0 4 CI CH2CH2CH2CH3 402,477 (55) 400,989 (55) Phenol, 4,4'-cyclohexylidenebis [2,6-dichloro- Phenol, 3,3'-methylenebis[2,4,6- t r ich loro- 83.0 51.1

-547- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure Repellency Index 404,111 Phenol, 2,3,5,6-tetrachloro- 94.0 (8) )H \Cl Cl 400,982 Phenol, 2,2'-thiobis[4-chloro- 95.4 (55) OH H< 401,944 Phenol, 2,2'-(2,2,2-trichloroethylidene)- 90.1 (55) bis[6-bromo-4-chloro- Br^ OH HO Br ^ ^ C H ( C C l 3 ) ^ ^ Cl Cl 400.997 Phenol. 2,2'-(2,2,2-trichloropthylidene)- 98.4 (55) bis[4,6-dichloro- Cl / \cH(CCl3 c r ^ ^ H 404,058 Phosphonic acid, (o-chloro- 85.2 (24) a-hydroxybenzyl)-, diethyl este;r [<*^^CHOHP(:0)(OC2H5)2 401,833 Phosphonic acid, (2,4-dichlorobenzyl)- 78.0 (74) CH2P(:0)(OH)2 Clr Cl

-548- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure 401.841 (74) 401,834 (74) Phosphonic acid, (2,4-dichlorobenzyl)-, diethyl ester CH2P(:0)(OC2H5)2 Repellency Index 67.0 Cl Phosphonic acid, (3,4-dichlorobenzyl)- CH2P(:0)(OH)2 Cl Cl 74.0 404,038 Phosphoric acid, tr is(2,3-dibromo- 94.7 (58) propyl) ester 0=P(OCH2CHBrCH2Br)3 403,293 Phosphoric acid, tris(pentachlorophenyl) 100.0 (53) ester 400,083 (29) (9) 402,217 (29) Cl̂ Cl Cl CI Cl -P(:0) -•3 Phthalic acid, tetrachloro- COOH Clj^' ' ' '%jCDOH Cl Phthalic anhydride, tetrachloro- Cl 67.8 74.3

-549- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure 500,705 (55) Phthalimide, N-ethyl- NC2H5 Repellency Index 90.0 500.727 (55) Phthalimide. N-isopropyl- O ICH(CH3)2 i=o 99.6 500.784 (55) Phthalimide, N-(m-nitrophenyl)- NO. 63.1 500,818 (55) Phthalimide, N-oc ty l - N(CH2)7CH3 1 = 0 87.6 404,107 Propane, 1.2-epoxy-3-(2.4.5-trichloro- 81.9 (8) phenoxy)- Cl CIL j«^^^OCH2CHCH2 l l ^ ^ C l \ o / 404,566 (1) 2 - Pr opanol, 1,1,1,3,3,3 -hexacblor o • CI3CCHOHCCI3 92.0

•550- RODENT CBC No. 404,530 (44) REPELLENCY TESTS (Continued) ^ame and Structure Propionic acid, 3,3'-thiodi-, bi8(l-methylheptyl) ester 404.529 (44) 404,526 (44) 404,078 (68) 404,076 (68) 404,077 (68) / S \ CH2 CH2 COOCH(CH3)(CH2) 5CH3 CH2CH2COOCH(CH3)(CH2)5CH3 Propionic acid, 3,3'-thiodi- dibutyl ester CH2 CH2 COO(CH2) 3CH3 \ CH2CH2COO(CH2)3CH3 Propionic acid, 3,3'-thiodi-, diethyl ester ^CH2CH2COOC2H5 I2CH2COOC2H5 Pyran, 3-bromo-2-ethoxytetrahydro- OC2H5 Repellency Index 54.5 Pyran, 3 -bromotetrahydro-2 -methoxy- Br OCH3 Pyran, 3,4-dibromo-2-ethoxytetrahydro- 65.3 64.5 65.8 57.8 100.0

-551- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure f 500,113 Pyrazole, 3,57dimethyl- (62) 4 - n i t r o s o - l - ( £ - t o l y l ) - Repellency Index 100.0 CH, 404,059-64 2-Quinizarinsulfonic acid, (7) manganese(II) salt 67.9 Mn 500,091-10 Quinoline, 8-amino-6-methoxy-, (13) monohydrochloride HCl 81.2 501,326-58 Salicylamide, copper(II) derivative (24) CONH, -€u 42 400.315 (44) Salicylic acid. 5-bromo- Br|' ' ' ' '^!^COOH L̂ OH 95.8 90.3

•552- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure 400,337 (24) Salicylic acid, 5-chloro- Cl j i ^ ' ^^COOH OH Repellency Index 100.0 400,312 (24) 500,854 (55) 506,413 (55) 403,636 (35) 400,890 (55) (18) Salicylic acid. 3.5-dichloro- Stearic acid. 2-phenylhydrazide NHNHCO(CH2)i£,CH3 Stilbene, 3,4-methylenedioxy- 2 ' ,4 ' -d in i t ro- \ = / Succinic acid, tetrafluoro- HOOCCF2CF2COOH 1,3,5,7-Tetroxocane, 2,6- bis(trichloromethyl) - Cl 99.4 55.0 17.5 9.0 45.5 503,607 (43) £-Toluidine, 3,5-dinitro- CH,^ *N02 NH, 78.0

•553- RODENT REPELLENCY TESTS (Continued) CBC No. Name and Structure 510,870 (44) £ - T r i a z i n e , 2,4-diamino-6-(2-furyl)- N . II ^ ^ 2 NH, Repellency Index 98.0 501,702-15 Urea, amidino-, monosulfate (3) H2NC(:NH)NHCONH2 ' H2SO4 500,766 (55) 108,771 (58) 404,523-54 (44) 401,860-61 (12) 404,466 (55) 401,047 (31) Valeric acid, 4-methyl- , 2 -phenylhydrazide o NHNHCOCH2CH2CH(CH3)2 d-Verbenol H3CCCH3 OH Xanthic acid, butyl- , ester with mercaptoacetic acid, calcium salt [CH3(CH2)30C(:S)SCH2C0032Ca Xanthic acid, sec-butyl-, potassium salt CH3CH2CH(CH3)OC(:S)SK Xanthic acid, t e r t -buty l - , arsenic(III) derivative [(CH3)3COCSS]3As Xanthic acid, ethyl- , anhydrosulfide with O-ethylthiolcarbonate 82.1 100.0 72.0 86.4 80.4 96.9 95.5 C2H50C(:S)SC(:0)OC2H5