Appendix B

Biographies

Dr. Isaf Al-Nabulsi (panelist) currently serves as Acting Director at the Office of Domestic and International Health Studies within the Office of Health and Safety, Office of Environment, Health, Safety and Security at the Department of Energy (DOE). Dr. Al-Nabulsi is responsible for managing and coordinating day-to-day activities associated with domestic and international health studies, including ensuring that office activities comply with departmental directives, regulations, and law. Dr. Al-Nabulsi continues to serve as Senior Technical Advisor to Director, Office of Health and Safety, and provides advice on a wide range of topics, including radiobiology and dosimetry, domestic and international health activities, radiation protection policy, computed tomography scanning for early lung cancer detection, and human subject research issues. In addition, she continues to serve as the Japan Program Manager. Dr. Al-Nabulsi joined DOE in 2008 in the Office of Former Worker Screening Programs. Prior to joining DOE, she served as a Program Administrator for the congressionally mandated Veterans Advisory Board on Dose Reconstruction for the Department of Defense and the Department of Veterans Affairs at the National Council on Radiation Protection and Measurements. She previously held a position as Senior Program Officer/Study Director with the Board on Radiation Effects Research at the National Research Council/National Academy of Sciences, where she directed 12 studies, 5 of which were congressionally mandated studies. Dr. Al-Nabulsi has more than 30 years of experience in radiation sciences. She received her M.S. in radiation sciences from Georgetown University and her Ph.D. in biomedicinal chemistry from the School of Pharmacy at the University of Maryland in Baltimore. She is also a graduate

of the Leadership for a Democratic Society Executive Leadership. She is a member of the Radiation Research Society, Health Physics Society, Health Physics Society International Committee, Health Physics Society Medical Response Subcommittee of the Health Physics Society Homeland Security Committee, Health Physics Society Radiation Research Needs Task Force, and Health Physics Society Women in Radiation Protection.

Ralph Andersen (committee member) was the Senior Director of Radiation Safety and Environmental Protection at the Nuclear Energy Institute (NEI) in Washington, DC. He represented the nuclear energy industry to Congress, the administration, federal agencies, and other national and international organizations on management and environmental protection. Prior to joining NEI in 1992, Mr. Andersen worked for 20 years in radiation protection in the areas of nuclear energy, research, education, and medicine. During that time, he has held such positions as Radiation Protection Manager at the Fermi 2 nuclear power plant, Director of Safety Assessment and Environmental Protection for the Detroit Edison Company, Radiation Safety Officer and Lecturer in the Department of Physics and Astrophysics at the University of Colorado, and Principal Researcher and Associate Radiation Safety Officer at the University of Maryland Medical Center. Mr. Andersen is certified as a health physicist by the American Board of Health Physics and is a U.S. delegate to the International Radiation Protection Association. He received his B.A. degree from the University of Maryland and has completed graduate studies in the Department of Radiation Biology and Radiology at Colorado State University.

Dr. Jeri Anderson (panelist) is a Health Physicist at the National Institute for Occupational Safety and Health (NIOSH) in Cincinnati, Ohio, a position she has held since June 2004. She is primarily responsible for performing retrospective radiation exposure assessment in support of epidemiological studies of workers occupationally exposed to radiation and radioactive materials. She also provides technical support to workplaces with radiological concerns and during radiological/nuclear emergency response and preparation activities.

Armin Ansari (panelist) is the Radiological Assessment Team Lead at the Centers for Disease Control and Prevention (CDC). He received his B.S. and Ph.D. in radiation biophysics from the University of Kansas and completed his postdoctoral research in radiation mutagenesis at Oak Ridge and Los Alamos National Laboratories. His focus since joining CDC in 2002 has been on public health preparedness and response planning for nuclear and radiological emergencies and he has led the development of key national guidance documents as well as numerous training programs directed at

public health professionals. He is a Fellow and Past President of the Health Physics Society and is certified in comprehensive practice by the American Board of Health Physics. He is also an elected member of the National Council on Radiation Protection and Measurements and serves as member of the U.S. delegation to the United Nations Scientific Committee on the Effects of Atomic Radiation.

Kimberly Applegate (panelist) is a Professor of Radiology and Pediatrics at the University of Kentucky in Lexington. Dr. Applegate is the Chair of Committee 3 of the International Commission on Radiological Protection (ICRP), focusing on radiation protection in medicine. Dr. Applegate is a leader in radiology: her policy and research work, including 200 publications, has resulted in an improved understanding of the structure, process, and outcomes of how pediatric imaging is practiced, including the volume of ionizing imaging in children, the variation in radiation dose in pediatric computed tomography, and the standardization of practice for both children and adults. She has worked collaboratively around the world across medical specialties and geographic boundaries to improve access to best practices. On the steering committee of the Image Gently Alliance from its start in 2007 to the present, she is dedicated to its mission to improve safe and effective imaging care of children worldwide. Dr. Applegate has received a number of awards that include the American Association for Women in Radiology’s Marie Sklowdoska Curie Award for her unique roles in leadership and outstanding contributions to the advancement of women in the radiology professions.

As Co-Director of Complex Adaptive Systems–Biomedicine at Arizona State University (ASU), Dr. Anna Barker (presenter) designs and implements new research knowledge networks, projects, and models to address major problems in biomedical research and biomedicine. She currently focuses on complex systems science as applied to the discovery and systems development of biomarkers, next-generation clinical trials, and the applications of artificial intelligence and advanced analytics for biomarker discovery. Prior to ASU, she served as the Deputy Director and Deputy Director for Strategic Scientific Initiatives for the National Cancer Institute (NCI)/National Institutes of Health (NIH), where she developed and led transdisciplinary programs such as the Nanotechnology Alliance for Cancer, The Cancer Genome Atlas (TCGA); Clinical Proteomics Technologies Initiatives and the Physical Sciences–Oncology Centers. She was founding Co-Chair of the NCI-Food and Drug Administration (FDA) Interagency Oncology Task Force, founding Co-Chair of the Cancer Steering Committee of the Foundation for the National Institutes of Health Biomarkers Consortium, and was responsible for NCI’s international cancer research programs. She was

a Senior Executive at Battelle Memorial Institute for 18 years, where as a Senior Vice and Group President she pioneered key initiatives in cancer research and biomedicine. Dr. Barker was also Co-Founder and Chief Executive Officer of a public biotechnology company focused on novel strategies to control reactive oxygen damage in inflammatory diseases and cancer. She serves on a number of boards of for-profit and nonprofit organizations, as chair of national committees, and in strategic advisory roles. She has also received a number of awards for her cancer research, policy, and advocacy efforts. Dr. Barker received her M.A. and Ph.D. at The Ohio State University, where she trained in immunology and microbiology.

Dr. Amy Berrington de González (presenter) is the Branch Chief and Senior Investigator in the Radiation Epidemiology Branch of the National Cancer Institute (NCI). She is an internationally recognized expert in the potential cancer risks from medical radiation exposures. Dr. Berrington de González is co-principal investigator of the UK Pediatric CT scans cohort, which was the first epidemiological study to suggest a direct link between computed tomography scans and subsequent cancer risk. She also leads studies on the risk of second cancer after proton therapy and other emerging radiotherapy techniques. Dr. Berrington de González is currently a member of the National Academy of Sciences’ Nuclear and Radiation Studies Board and has participated in many national and international radiation committees. She is an elected member of the American Epidemiological Society and served on the editorial board for the American Journal of Epidemiology. Before joining NCI in 2008 she held faculty positions at Oxford and Johns Hopkins University.

Eleanor A. Blakely (presenter) is a graduate of the University of San Diego, California (B.A. in biology with chemistry minor), and the University of Illinois at Urbana-Champaign, Illinois (M.S. in biophysics and Ph.D. in physiology). Dr. Blakely has spent her entire professional career at the Lawrence Berkeley National Laboratory (LBNL), where she is a Senior Staff Biophysicist with more than 44 years of professional experience in molecular, cellular, and animal radiobiological research directed at studying the basic mechanisms of radiation responses, with an emphasis on charged particle radiation effects. She also holds a faculty affiliate appointment in the Department of Radiological Health Sciences at Colorado State University, Fort Collins, Colorado, and is a Clinical Professor of radiation medicine (nontenured) at Loma Linda University, School of Medicine, Loma Linda, California. Her professional activities have included service on advisory panels for several hospitals, universities, the National Academy of Sciences, and numerous federal agencies including the Department of Energy, the National Institutes of Health, and the National Aeronautics and Space

Administration and the Department of Defense. In June 2015 she retired after 40 years at LBNL, but was rehired by LBNL in October 2015, and continues to work part time. In 2015 she received the Berkeley Laboratory Director’s Award for Exceptional Achievement: the Berkeley Lab Citation Award. Dr. Blakely is a Fellow of the American Association for the Advancement of Science, a recipient of the Distinguished Service Award of the Radiation Research Society, and a Distinguished Emeritus Member of the National Council on Radiation Protection and Measurements.

Dr. Steve Blattnig (panelist) has been working on many aspects of space radiation research for the past 20 years. He graduated from the University of Wisconsin–Milwaukee with a Ph.D. in physics, and his graduate work comprised the development of a pion and muon radiation transport code, including the associated particle production cross-section modeling. In January 2003 he began work as a physicist at the National Aeronautics and Space Administration (NASA) Langley Research Center. His major areas of research have included the development of space radiation transport methodologies, nuclear and particle physics modeling and their application to mission analysis and vehicle design, and the development of radiation shielding materials. He has also been integral to the development of validation methodologies and on the use of model results in decision making. He is one of the primary authors of the NASA Standard for Models and Simulations, NASA-STD-7009. More recently, his focus has been on the development of probabilistic risk methodology and radiation biology modeling for effects including cancer, cardiovascular disease, and acute radiation syndrome. He was the project manager for the space radiation transport and measurement project and was the principal investigator of the space radiation risk assessment project.

Mike Boyd (panelist) is the Director of the Center for Science and Technology in the Environmental Protection Agency’s Office of Radiation and Indoor Air/Radiation Protection Division. The Center is responsible for the development of radiation dose and risk assessment guidance and for providing technical support for radiation protection policy issues. Mr. Boyd is also the Co-Chair of the Federal Guidance Subcommittee of the Interagency Steering Committee on Radiation Standards. He is a member of the National Council on Radiation Protection and Measurements’ (NCRP’s) PAC 5 and was recently elected to the NCRP Board of Directors. He is a member of the International Commission on Radiological Protection (ICRP) Committee 4 and chairs ICRP Task Group 98 on Application of the Commission’s Recommendations to exposures resulting from contaminated sites from past industrial, military, and nuclear activities. Since 2015, he has chaired the Organisation for Economic Co-operation and Development/

Nuclear Energy Agency’s Committee on Radiological Protection and Public Health. Mr. Boyd is an active member of the Health Physics Society and is a delegate to the International Radiation Protection Association, where he is currently a member of its International Congress Program Committee for IRPA 15, which will be held in Seoul, Korea, in May 2020. He has a B.S. in biology and an M.S. in public health from the University of North Carolina at Chapel Hill.

David Brenner (presenter) is the Director of the Columbia University Center for Radiological Research, which is the oldest and largest radiation biology center in the United States. He is also Principal Investigator of the Center for High-Throughput Minimally-Invasive Radiation Biodosimetry, a multiinstitute consortium to develop high-throughput biodosimetry technology to rapidly test individual radiation exposure after a radiological incident. He is also Director of the Columbia Radiological Research Accelerator Facility, which is a national facility dedicated to probing the mechanisms of radiation-induced cancer. Dr. Brenner’s research focuses on mechanistic models for the effects of ionizing radiation on living systems. He divides his research time between the effects of high doses of ionizing radiation (relating to radiation therapy) and the effects of low doses of radiation (relating to radiological, environmental, and occupational exposures). At low doses, he was the first to quantify the potential risks associated with the rapidly increasing usage of computed tomography scans in the United States. At high doses, his proposal to use large-fraction radiotherapy for prostate cancer (hypofractionation) is increasingly being used in the clinic. Dr. Brenner has published more than 350 peer-reviewed papers; in addition, he is the author of two books on radiation for the lay person: Making the Radiation Therapy Decision and Radon, Risk and Remedy. He is a recipient of the Failla Gold Medal, the annual award given by the Radiation Research Society for contributions to radiation research.

James A. Brink, M.D. (committee member and session moderator), is Chief of Radiology at Massachusetts General Hospital (MGH) and the Juan M. Taveras Professor of Radiology at Harvard Medical School. Dr. Brink has expertise and broad experience in medical imaging, including utilization and management of imaging resources and monitoring and control of medical radiation exposure. Before joining MGH, Dr. Brink was an associate professor at the Mallinckrodt Institute of Radiology at Washington University School of Medicine and professor and chair of the Yale Department of Diagnostic Radiology. He is a Fellow of the Society for Computed Body Tomography/Magnetic Resonance, Past President of the American Roentgen Ray Society, Fellow and Chair of the Board of Chancellors of the American College of Radiology, and scientific vice-president and member

of the Board of Directors of the National Council for Radiation Protection and Measurements. He earned his M.D. degree at Indiana University and completed his medical residency and fellowship at MGH.

Terry A. Brock (panelist) is a Senior Health Physicist with the U.S. Nuclear Regulatory Commission (USNRC), where he has worked for more than 16 years. He has served as the USNRC Program Manager for the Radiation Exposure Information and Reporting System, the Analysis of Cancer Risks in Populations near Nuclear Facilities study, and the lead for the agency’s participation in the One Million U.S. Radiation Workers and Veterans Heath Study. He is a current management board member and past Vice Chair of the Organisation for Economic Co-operation and Development/ Nuclear Energy Agency’s Information System on Occupational Exposure program. He is the agency liaison with the National Council on Radiation Protection and Measurements and the International Commission on Radiological Protection and serves as the USNRC representative on the Executive Committee of the Joint Coordinating Committee for Radiation Effects Research (Russian Health Studies). He has served as the project manager for the State-of-the-Art Reactor Consequence Analyses study and on the Risk Task Group that explored risk-informing the radioactive materials arena. Before USNRC, he worked in health physics at a commercial nuclear power facility and at two universities. In addition to health physics, Dr. Brock has worked on environmental health and risk communication issues related to pesticides and hazardous substance cleanup sites. Dr. Brock holds a Ph.D. in public health and M.S. in radiation heath physics and environmental health from Oregon State University. He holds a B.S. in health physics and industrial hygiene from Purdue University.

Antone L. Brooks (presenter) graduated from Dixie Junior College, received his B.S. and M.S. from The University of Utah and a Ph.D. from Cornell University. He is a retired professor from Washington State University. He served on the National Council on Radiation Protection and Measurements for almost 30 years and was on the Board of Directors for that organization, was a member of the Environmental Protection Agency Science Advisory Board, was on the National Academy of Sciences team that produced the BEIR VI report on Radon Health Effects, and was the Chief Scientist for the Department of Energy Low Dose Radiation Research Program. He recently published the book Low Dose Radiation: The History of the U.S. Department of Energy Research Program. He has published more than 200 peer-reviewed articles and served on many national and international review groups.

Dr. Donald A. Cool (panelist) is currently the Technical Executive for Radiation Safety with the Electric Power Research Institute (EPRI), working with member utilities on occupational, public, and environmental issues. Before joining EPRI, Dr. Cool served in various senior management and advisory positions with the U.S. Nuclear Regulatory Commission. Dr. Cool is a member of the Main Commission of the International Commission on Radiological Protection and the Chair of Committee 4 on Application of the Commission’s Recommendations. He is a Council Member of the U.S. National Council on Radiation Protection and Measurements and was Co-Chair of Council Committee 1 on Radiation Protection Recommendations. Dr. Cool has more than 36 years of experience in radiological protection and is a Fellow of the Health Physics Society.

Dr. Francis A. Cucinotta (presenter) is a Professor of Health Physics at the University of Nevada, Las Vegas (UNLV). He received his doctorate in nuclear physics from Old Dominion University during 1988. He worked at the National Aeronautics and Space Administration (NASA) from 1990 to 2013 in several positions including research scientist, radiological health officer for spaceflight, and manager and chief scientist for the Space Radiation Research Project. Dr. Cucinotta was NASA’s manager for the construction and operation of the NASA Space Radiation Lab at Brookhaven National Laboratory. He developed the astronaut exposure database of organ doses, and cancer risk estimates for all human missions from Mercury to the International Space Station. He has developed models of cancer, circulatory disease, and noncancer risks to the blood-forming organs and central nervous system for understanding the risks to cancer patients and radiation workers. He led NASA’s biodosimetry program for the International Space Station and discovered the association of increased incidence of cataracts in past space missions. Dr. Cucinotta’s biophysical models are applicable to radiation exposures on Earth, to radiation workers and patients, and for astronauts in space. He developed space radiation quality factors and risk models that were approved for use at NASA. The National Research Council and the National Council on Radiation Protection and Measurements (NCRP) have reviewed his work in dedicated reports. Dr. Cucinotta has published 370 peer-reviewed journal articles, numerous book chapters, and NASA technical reports on nuclear and space physics, shielding, DNA damage and repair, biodosimetry, systems biology, cancer, and central nervous system risk assessment models. He has won research grants from NASA, the Department of Energy, and the National Cancer Institute. He earned numerous NASA awards for his efforts, and received the 2015 Scholar award from the School of Allied Health Sciences and UNLV’s 2018 Barrick Scholar Award. Dr. Cucinotta served as president of the Radiation Research Society during 2014 and

received its highest scientific achievement award, the Failla Award, during 2018. He is serving a second, 6-year term as an elected council member of NCRP, and has served on special committees for NCRP and the International Commission on Radiological Protection.

Lawrence T. Dauer, Ph.D., DABHP (panelist), is a Medical Health Physicist specializing in radiation protection at Memorial Sloan Kettering Cancer Center. He is an Associate Attending Physicist in the Departments of Medical Physics and Radiology and serves as the Corporate Radiation Safety Manager and Chair of the Emergency Management Committee Officer. He has spent more than 30 years in the field of radiation protection and health physics, including radiation protection programs for nuclear energy and industrial sectors as well as operations and research in medical health physics. Dr. Dauer served as Chair and Vice Chair of the Radiation Safety Committee of the American Association of Physicists in Medicine, President and Executive Council Member of the Medical Physics Section of the Health Physics Society, President of the Greater NY Chapter of the HPS, and Board Member of the Radiological and Medical Physics Society of New York, as well as a member of the International Commission on Radiological Protection Committee 3–Radiation Protection in Medicine. He is currently a council and board member of the NCRP and a member of the Science Committee of the International Organization for Medical Physics. Dr. Dauer has received both the Elda Anderson and the Fellow Award from the Health Physics Society. He was Co-Chair of the National Council on Radiation Protection and Measurements (NCRP) SC 1-23, which produced NCRP Commentary No. 26–Guidance on Radiation Dose Limits for the Lens of the Eye. He was also Co-Chair of NCRP SC 1-25, which produced NCRP Commentary No. 27–LNT and Radiation Protection.

Sadik Esener (presenter) is the Director of the Oregon Health & Science University (OHSU) Knight Cancer Institute Cancer Early Detection Advanced Research Center, the Wendt Family Endowed Chair in Early Cancer Detection, and Professor in the Biomedical Engineering Department at OHSU. His research focus has involved projects in multiple scientific fields relevant to cancer early detection, including electrical and optical engineering, nano-engineering, and material sciences for biomedical applications. In addition, he has made many pioneering contributions to the fields of optical interconnects, light modulation, optical data storage, biophotonics as applied to gene chips, cell sorting and manipulation, and heterogeneous integration of photonics, electronics, and biological components. More recently his work has focused on the synthesis and application of nanoparticles delivery of biologics for cancer therapies, brain mapping, and in vivo imaging. Dr. Esener received his Ph.D. in applied physics and electrical

engineering from the University of California, San Diego. He has published more than 375 journal and conferences articles and made more than 250 presentations in international scientific meetings, 60 of which were invited. He holds 23 issued patents, has authored several book chapters, and organized and chaired scientific international conferences. Dr. Esener co-founded and served on the board of directors and scientific advisory boards of several companies.

Dr. Silvia Formenti (presenter) is the Chair of Radiation Oncology at Weill Cornell Medical College and the Associate Director of the Cancer Center. Trained as a medical and radiation oncologist, she devoted her career to translate novel preclinical information to the clinic. Key to her formation was a year spent in Malcolm Mitchell’s laboratory at the University of Southern California, in cancer immunology. Her initial research on how to best combine radiation and systemic therapy, both pre-clinically and clinically, evolved on focusing on the systemic effects of radiotherapy, particularly on the immune system. Her laboratory’s original demonstration that the abscopal effect of radiotherapy is immune mediated has opened a fertile field of research to understand the immune-stimulatory and immune-suppressive effects of ionizing radiation, and to develop strategies directed at harnessing anti-tumor immunity in irradiated subjects. This work has introduced a paradigm shift in radiation and cancer biology. In this novel application, radiotherapy contributes to recovering an immunological equilibrium in the setting of metastatic cancer, by converting an irradiated metastasis into an in situ, individualized vaccine in the presence of immune checkpoint blockade (anti-CTLA4, anti-PDL-1). Once successfully immunized against the irradiated site, the host can develop an anti-tumor immune response capable of rejecting the other metastases. In some patients with metastatic disease the combination of radiation and immune checkpoint blockade has resulted in complete remissions, sustained for years after treatment (without any other additional interventions). Dr. Formenti’s work has been funded by grants from the National Institutes of Health, the Department of Defense, the American Cancer Society, and the Breast Cancer Research Foundation and is currently leading four investigator-initiated clinical trials of immunotherapy and radiotherapy.

Albert J. Fornace, Jr., M.D. (presenter), is a Professor in the departments of Oncology; Biochemistry and Molecular & Cellular Biology; and Radiation Medicine at Georgetown University. He was the first recipient of the Molecular Cancer Research Chair at Lombardi Comprehensive Cancer Center, joining Georgetown in 2006 from the Harvard School of Public Health, where he was the director of the John B. Little Center for the Radiation Sciences and Environmental Health. Earlier, he was Chief of the Gene

Response Section at the National Cancer Institute. He is the 2015 recipient of the Radiation Research Society Failla Gold Medal.

Research from the Fornace Laboratory has included discovery of some of the first radiation-inducible genes including the gadd gene group of growth-arrest and DNA-damage inducible genes. His studies in this area led to the landmark paper where they and their collaborators at Johns Hopkins demonstrated the radiation-responsive ATM-p53-Gadd45a pathway, and showed for the first time that p53 could bind and induce a cellular gene. This was followed by a large series of important reports by their laboratories and others that elucidated the major contribution of the tumor suppressor p53 as a transcription factor in its role as a “guardian of the genome.” Dr. Fornace’s research has shown that stress-related signals inside the cell alter the expression of multiple genes involved in cell-cycle control, programmed cell death, DNA damage processing, metabolism, and pro-inflammatory signaling, among others. Radiation signaling events were shown by his laboratory to occur at surprisingly low doses of radiation. His laboratory has contributed to our understanding of the key roles for important stress-signaling pathways in cancer prevention as well as their perturbations that contribute to tumor development after exposure to radiation. His radiobiology studies also include high-energy ion radiation, where he leads a National Aeronautics and Space Administration Specialized Center of Research in gastrointestinal carcinogenesis by low dose space radiation. In addition to his research on the molecular pathways of radiation-inducible genes, Dr. Fornace has also studied cellular stress responses at broader levels. His laboratory at the National Cancer Institute was the first in collaboration with the National Human Genome Research Institute to assess genome-wide responses to radiation using a transcriptomics approach. His omics studies were then extended to the small-molecule level (i.e., metabolomics) and his team along with collaborators developed the field of radiation metabolomics and have demonstrated low dose radiation effects at the metabolomic level. Dr. Fornace currently directs the Waters Center of Innovation for Metabolomics at Georgetown.

Dr. Charles Gawad (presenter) is an Assistant Member in the Departments of Oncology and Computational Biology at St. Jude Children’s Research Hospital. He received his medical degree from the University of Arizona in 2006, followed by clinical training in pediatrics and pediatric oncology at the University of California, Los Angeles, and Stanford University, respectively. He then received a Ph.D. in cancer biology from Stanford in the laboratory of Patrick O. Brown, followed by postdoctoral training in the Department of Bioengineering under the mentorship of Stephen Quake. His laboratory focuses on the development and application of new technologies to improve human health, with a focus on single-cell genomics. He is a

recipient of the Scholar Award from the American Society of Hematology, Special Fellow Award from the Leukemia and Lymphoma Society, Career Award for Medical Scientists from the Burroughs Wellcome Fund, and the National Institutes of Health Director’s New Innovator Award.

Hailing from San Antonio, Texas, John Gilstad (panelist) graduated from the U.S. Naval Academy in May 1987 with a bachelor’s degree in English and proceeded to medical school at the Uniformed Services University of the Health Sciences. Following initial postings in Quantico, Virginia, and Roosevelt Roads, Puerto Rico, he completed a clinical fellowship in geriatrics at Johns Hopkins University and worked as an internist and geriatrician at the National Naval Medical Center, and aboard USNS COMFORT in support of Operation Iraqi Freedom. Following a tour at Naval Hospital Yokosuka, Japan, he reported to the Armed Forces Radiobiology Research Institute (AFRRI) in 2009 for a 3-year assignment as Department Head for Scientific Research. Captain Gilstad was subsequently selected as Executive Officer of the Navy Medical Research Unit 2 (NAMRU-2) in Hawaii and Singapore, and as Commanding Officer of NAMRU-3 in Cairo, Egypt, both of which focused on infectious disease surveillance and regional partnerships for capacity building and scientific collaboration. Returning to AFRRI from Cairo, Captain Gilstad served as Chief, Military Medical Operations, before being selected as Institute Director, beginning April 2018. His current lines of effort at AFRRI include strategic integration of the AFRRI directed-science mission into USU and new approaches to the military problems of radiological and nuclear medical readiness.

Jenny Goodman (panelist) obtained a B.S. in biochemistry from Rutgers University in 1980 and an M.S. in radiation science from Rutgers University in 1987. Ms. Goodman has been with the New Jersey Department of Environmental Protection (DEP) since 1985 and prior to that she was a health physicist with the Environmental Protection Agency. At DEP, Ms. Goodman has worked on nuclear emergency response, radon, radiologically contaminated site evaluations, decommissioning, radioactive materials licensing and inspection, and radionuclides in water. She is currently the manager of the Bureau of Environmental Radiation at DEP.

Joe W. Gray (committee chair, presenter, and session moderator) is the Director, Oregon Health & Science University Center for Spatial Systems Biomedicine, and Associate Director for Biophysical Oncology, Knight Cancer Institute. He applies -omic and multi-scale molecular imaging technologies to elucidate mechanisms by which cancers arise, progress, and become resistant to treatment and uses this information to develop therapeutic strategies to more durably control cancers with emphasis on breast cancer.

He serves on the Board of Counselors for the Radiation Effects Research Foundation. He has more than 500 publications and 80 U.S. patents. Major awards include the E.O. Lawrence Award, Department of Energy; the Curt Stern Award, American Society for Human Genetics; the Alfred G. Knudson Award in Cancer Genetics, National Cancer Institute; election as a Fellow of the American Institute for Medical and Biological Engineering and the American Association for Cancer Research; and election to the National Academy of Medicine.

Dan Greenbaum (presenter) is President and Chief Executive Officer of the Health Effects Institute (HEI). In that role, Mr. Greenbaum leads HEI’s efforts, supported jointly by government and industry, to provide public and private decision makers—in the United States, Asia, Europe, and Latin America–with high-quality, impartial, relevant, and credible science about the health effects of air pollution to inform air quality decisions in the developed and developing world. Mr. Greenbaum has been a member of the U.S. National Academies’ Board of Environmental Studies and Toxicology and vice-chair of its Committee for Air Quality Management in the United States. He is currently serving on the National Academies’ Committee for the Environmental Health Matters Initiative and recently served on the National Academies’ Committee on Grand Challenges for Environmental Engineering. In May 2010, Mr. Greenbaum received the Thomas W. Zosel Outstanding Individual Achievement Award from the Environmental Protection Agency for his contributions to advancing clean air and in June 2017 he received the Haagen Smit Award from the California Air Resources Board for his and HEI’s contributions to air pollution science and policy. Mr. Greenbaum has more than four decades of governmental and nongovernmental experience in environmental health. Just prior to coming to HEI, he served as Commissioner of the Massachusetts Department of Environmental Protection, where he was responsible for the Commonwealth’s response to the Clean Air Act, as well as its award-winning efforts on pollution prevention, water pollution, and solid and hazardous waste. Greenbaum holds bachelor’s and master’s degrees from the Massachusetts Institute of Technology in city planning.

Janet Hall, Ph.D. (presenter), is a Research Director at INSERM (the French National Institute of Health and Medical Research). Before moving to the Cancer Research Centre of Lyon in January 2015, she was Director of the Unit of Genotoxicology, Signalisation and Experimental Radiotherapy at Institut Curie in Orsay, France, and from 1999 to 2006 she was head of the DNA Repair Team at the International Agency for Research in Cancer (IARC) in Lyon, where she had been an IARC research scientist since 1988. Her research focuses on the impact on cancer risk of the modulation of

DNA repair processes by genetic and environmental factors and viral infections, and how these changes can be exploited for therapeutic purposes. She was a member of the High Level Expert Group on European Low Dose Risk Research and is a co-author of several reviews on biomarkers for low dose ionizing radiation exposure.

Kathryn D. Held (panelist) is President of the National Council on Radiation Protection and Measurements (NCRP) after being the NCRP Executive Director and Chief Science Officer from 2016 to 2018, on the NCRP Board of Directors from 2008 to 2014, and on a number of NCRP committees. Dr. Held is also associate radiation biologist in the Department of Radiation Oncology, Massachusetts General Hospital, associate professor of radiation oncology at Harvard Medical School, and Distinguished Visiting Professor at Gunma University, Japan. Dr. Held’s research interests are in molecular mechanisms for the induction of cell-cell signaling by radiation, including high-energy particles, and characterization of charged particle-induced DNA damage responses and cell killing. Dr. Held also teaches radiation biology to radiation oncology medical and physics residents and graduate students. Dr. Held earned her Ph.D. from The University of Texas at Austin. She has served on review panels and committees for numerous federal agencies including the National Institutes of Health, the National Aeronautics and Space Administration, the Department of Energy, the Department of Defense, and other organizations such as the Radiological Society of North America and the National Academy of Sciences.

Dr. Nolan Hertel (panelist) is a Professor of nuclear and radiological engineering at the Georgia Institute of Technology. He earned his B.S. and M.S. in nuclear engineering from Texas A&M University and his Ph.D. from the University of Illinois at Urbana-Champaign. He previously served as a faculty member at The University of Texas at Austin from 1979 to 1992. Dr. Hertel is currently the President of the Health Physics Society (HPS). He received the HPS Distinguished Scientific Achievement Award in 2016 and the American Nuclear Society Radiation Protection and Shielding Division’s Rockwell Lifetime Achievement Award. Dr. Hertel holds a joint faculty appointment in the Center for Radiation Protection Knowledge at Oak Ridge National Laboratory. He is also an affiliated faculty of the Georgia Tech Center for International Strategy, Technology and Policy of the Sam Nunn School of International Affairs.

Professor Randy Jirtle (presenter) headed the epigenetics and imprinting laboratory at Duke University until 2012. He is now a professor of epigenetics in the Department of Biological Sciences at North Carolina State University, Raleigh, North Carolina, and a senior scientist in the McArdle

Laboratory for Cancer Research at the University of Wisconsin, Madison. Mr. Jirtle’s research interests are in epigenetics, genomic imprinting, and the fetal origins of disease susceptibility. He has published more than 200 peer-reviewed articles and was a featured scientist on the NOVA television program on epigenetics entitled Ghost in Your Genes. He was honored in 2006 with the Distinguished Achievement Award from the College of Engineering at the University of Wisconsin–Madison. In 2007, Mr. Jirtle was nominated for Time Magazine’s Person of the Year. He received the Linus Pauling Award from the Institute of Functional Medicine in 2014. In 2019 he received the Alexander Hollaender Award from the Environmental Mutagenesis and Genomics Society.

Dmitry Klokov (presenter) obtained a Ph.D. in radiobiology from Moscow State University in 2000. He is currently a Head of the Radiobiology Section at Canadian Nuclear Laboratories and an Adjunct Professor at the Department of Biochemistry, Microbiology and Immunology of the University of Ottawa. He has published more than 45 papers in peer-reviewed literature. His research interests encompass various fields of radiobiology, including effects of low doses on DNA damage and repair, epigenetics, microenvironment, and carcinogenesis in somatic and stem cells.

Ourania (Rania) Kosti, Ph.D. (staff member), is a Senior Program Officer at the Nuclear and Radiation Studies Board (NRSB) of the National Academies of Sciences, Engineering, and Medicine. Dr. Kosti’s interests within the NRSB focus on radiation health effects, and she is the Principal Investigator for the National Academies’ Radiation Effects Research Foundation Program that supports studies of the atomic bombing survivors in Japan. Prior to her current appointment, she was a postdoctoral fellow at the Lombardi Comprehensive Cancer Center at Georgetown University Hospital in Washington, DC, where she conducted research on biomarker development for early cancer detection using case-control epidemiological study designs. She focused primarily on prostate, breast, and liver cancers and trying to identify those individuals who are at high risk of developing malignancies. Dr. Kosti also trained at the National Cancer Institute (2005–2007). She received a B.S. in biochemistry from the University of Surrey, United Kingdom, an M.S. in molecular medicine from the University College London, and a Ph.D. in molecular endocrinology from St. Bartholomew’s Hospital in London, United Kingdom.

Michaela Kreuzer (committee member, presenter, and session moderator) obtained a diploma in statistics from the Ludwig-Maximilians-University (LMU) in Munich in Germany in 1987 and a Ph.D. in epidemiology in 1996. Since 2004 she has been member of the Medical Faculty of the LMU

(“Habilitation”) and a private teacher (Priv.-Doz.) in epidemiology. Dr. Kreuzer started her scientific career in 1988 as an epidemiologist at the Institute of Occupational Medicine, Heinrich-Heine University of Düsseldorf. In 1990 she moved into the research field “indoor radon and lung cancer” at the University of Wuppertal, Germany, and the Institute of Epidemiology at the HelmholtzZentrum Munich, Germany. Since 1998 she has worked at the Federal Office for Radiation Protection in Neuherberg in Germany, where she was previously heading the working group “Radiation Epidemiology” and is now heading the division “Effects and risks of ionizing and non-ionizing radiation.” She is principal investigator of the German uranium miner cohort study with nearly 60,000 radon-exposed miners. Dr. Kreuzer is a member of the European research platform Multidisciplinary European Low Dose Initiative, which was founded in 2010. From 2014 to 2017 she was Chair of the working group Strategic Research Agenda, and since 2018, Vice-Chair.

In the years since being diagnosed with renal cell carcinoma in 1997, Mike Lawing (panelist) has become very involved with cancer survivorship and advocacy for patients and their caregivers in a number of ways. He frequently challenges the newly diagnosed and their families that he encounters with a statement by Dr. Norman Cousins: “Don’t deny the diagnosis; try to defy the outcome.” Lawing is a co-host of the Powerful Patient Inc., an Internet podcasting organization dealing with medical issues of interest, and is co-chair of the Patient Advisory Board of KCCure. He has served as a member of the Board of Directors of The Kidney Cancer Association (KCA) and is the author of the KCA book We Have Kidney Cancer: Survivor Stories. He serves regularly as a consumer reviewer for the Department of Defense Peer-Reviewed Cancer Research Program; has served as a National Cancer Institute SPORE Grant Review panelist; served as a patient advocate on a joint SPORE application for M.D. Anderson, the University of North Carolina, and Stanford; and is an affiliate member of the American Association for Cancer Research and an alumnus of their Scientist-Survivor Program. He has served on the Patient Advisory Committee for one of the largest pharmaceutical companies, has given presentations and served on panels of numerous cancer organizations including the International Kidney Cancer Coalition and the National Comprehensive Cancer Network, and has served on several committees with the North Carolina Comprehensive Cancer Program and the South Carolina Cancer Alliance. He was a facilitator for Survivin’, a general cancer and caregiver support group at the Rutherford Regional Cancer Outreach Center, and is actively involved with several cancer support groups in the Carolinas. In addition to his involvements with cancer organizations and survivorship issues at several levels, Mr. Lawing is active in his community; conducting

programs for the elderly and the terminally ill at local rest homes and the area Hospice House as well as making presentations on cancer awareness, caregiving and survivorship, and related topics to local and regional organizations, support groups, churches, and other venues. Since 1977 he has been a volunteer with The Church of The Exceptional, Henrietta, North Carolina, a church for the physically and mentally challenged—one of the few ministries of its kind in the United States.

Dr. Ted Lazo (presenter) holds bachelor’s and master’s degrees in nuclear engineering and a Ph.D. in radiation protection, and has been focused in all his professional positions on the practical application of knowledge and experience. His experience has included applied decommissioning at Three Mile Island, environmental restoration at contaminated Department of Energy sites, operating laboratory and accelerator radiation protection at Brookhaven National Laboratory, and operational radiation protection at French nuclear power stations with FRAMATOME (now AREVA) and the French Electricity Utility (EDF). Since 1993 he has been with the Nuclear Energy Agency’s (NEA’s) Division of Radiation Protection and Radioactive Waste Management, where he is the Scientific Secretariat of NEA’s Committee on Radiation Protection and Public Health and is responsible for all subgroups (totaling approximately 250 experts from 33 countries). His work at NEA has focused on the evolution of the system of radiological protection, radiological risk assessment and management, radiological protection technical and social science, stakeholder involvement and risk governance, radiation protection policy and regulation, nuclear emergency management, occupational exposure at nuclear power plants, and decommissioning. He was the Chair of the International Congress Programme Committee for IRPA13 (Glasgow, May 13–18, 2012), and has participated in the work of International Commission on Radiological Protection (ICRP) Committee 4 as an observer from 1995 to 2017 (as a member of various Task Groups that developed ICRP Publications 101, 109, 111, 124, and 125).

Dr. Brian Marples (panelist) has more than 25 years of research experience in the field of radiation biology. In 2016, he relocated to the Department of Radiation Oncology at the University of Miami to become the Director of Radiobiology. His research interests focus on the molecular radiation response of tumor cells and normal tissues, with an emphasis on the biological mechanisms activated by exposure to low and clinically relevant doses of radiation, and how these events regulate cell death pathways. He served as the Biology Chair of the American Society for Therapeutic Radiology and Oncology (ASTRO) Education Committee and Science Education Program Development committee and sits on the ASTRO Science Council Steering Committee. He served as the Biology Chair of American College

of Radiology Radiation Oncology In-Training Examination committee and now sits on the American Board of Radiology Radiation Oncology Biology Committee. He became the Senior Biology Editor of the International Journal of Radiation Oncology Biology Physics (Red Journal) in October 2016.

John Neumann (presenter) is a Managing Director of the Government Accountability Office’s (GAO’s) new Science, Technology Assessment, and Analytics team, whose work is focused on supporting the science and technology needs of Congress by conducting technology assessments, providing oversight of federal science and technology programs, and developing innovative analytical techniques for carrying out audits and evaluations. Mr. Neumann is a 30-year veteran of GAO. Before taking on his current role, he was the Director of Science and Technology Issues within GAO’s Natural Resources and Environment (NRE) team. Under his leadership, this portfolio of work grew to include a broad array of products evaluating the management of the substantial federal investment in research and development, as well as federal agencies’ implementation of an array of programs, policies, and activities to protect intellectual property rights, enhance U.S. competitiveness, and stimulate the adoption of innovative technologies. Examples of current and recent work in this portfolio, which Mr. Neumann continues to lead, include the cost and schedule performance of National Science Foundation construction projects, such as telescopes and research ships; reviews of the policies and procedures for federal science agencies to maintain scientific integrity and for science agencies to more effectively deal with allegations of sexual harassment among grant recipients; and considerations for maintaining U.S. competitiveness in transformational research areas, such as quantum computing and synthetic biology. Mr. Neumann has received numerous awards, including, most recently, a Distinguished Service Award in 2018 in recognition of his exemplary leadership of NRE’s Science and Technology Issue area and his commitment to valuing all people. Prior to leading GAO’s science and technology oversight work, Mr. Neumann was an assistant director with the agency’s Contracting and National Security Acquisitions team, where he managed a diverse portfolio covering government-wide contracting and the U.S. defense industrial base. In particular, he became a recognized expert on export control issues and the protection of militarily critical technology, and the body of work he led resulted in the creation of a High Risk area in 2007 on ensuring the effective protection of technologies critical to U.S. national security interests. Earlier in his career, Mr. Neumann spent a year as a detailee to GAO’s Office of General Counsel and 1 year with the Senate Governmental Affairs Committee, where he conducted investigations for the Permanent Subcommittee on Investigations. Mr. Neumann earned a bachelor of arts in political science from the State University of New York at Stony Brook.

He also holds a juris doctor from Georgetown University Law Center and a master’s in business administration from American University.

CAPT Michael A. Noska (panelist) is the Senior Advisor for Health Physics, the Agency Radiation Safety Officer, and the Team Lead for Radiological Emergency Response at the Food and Drug Administration (FDA). He has been a health physicist with the U.S. Public Health Service (PHS) for 27 years and has had multiple assignments at the National Institutes of Health and FDA with a focus on internal radiation dosimetry and radiological emergency preparedness and response. Prior to joining PHS, Captain Noska worked as a research assistant in radiopharmaceutical laboratories at Harvard Medical School and Duke University Medical Center developing radiolabeled monoclonal antibodies for the treatment of cancer. He received his M.S. from the University of North Carolina School of Public Health as a Department of Energy Applied Health Physics Fellow. Captain Noska is a member of the National Council on Radiation Protection and Measurements. He is also the current Chair of the Federal Advisory Team for the Environment, Food and Health and a member of the Federal Radiological Preparedness Coordinating Committee. He is a past Chair of the Environmental Health Officer Professional Advisory Committee to the U.S. Surgeon General and past President of the Baltimore-Washington Chapter of the Health Physics Society. Captain Noska serves on several inter-agency committees and workgroups related to radiological emergency response. In 2011, he deployed to Japan as part of a team from the Department of Health and Human Services in support of the U.S. ambassador following the Great Tohoku Earthquake and the nuclear crisis at the Fukushima Daiichi Nuclear Power Station.

Dale L. Preston, Ph.D. (presenter), is a biostatistician with almost 40 years of experience describing and quantifying the long-term health effects of radiation in humans. He played a central role in developing the modern methods and tools used to characterize radiation effects and has authored or co-authored more than 200 peer-reviewed scientific publications. Between 1981 and 2004, while living in Hiroshima, Dr. Preston worked on studies of Hiroshima and Nagasaki atomic-bomb survivors at the Radiation Effects Research Foundation and remains active in the Foundation’s research. Since 1987 he has been involved in studies of various Russian populations, initially Chernobyl victims, but primarily people exposed to radiation as a result of the operations of the Russian reactor and plutonium production complex (Mayak). He has served as a consultant for the United Nations Scientific Committee on the Effects of Atomic Radiation, the U.S. National Academy of Sciences’ Committee on the Biological Effects of Ionizing Radiation, and other groups around the world. Dr. Preston is a Fellow of

both the American Statistical Association and the American Association for the Advancement of Science. In 2017 he received the Radiation Research Society’s Failla Award in recognition of a history of significant contributions to radiation research. Dr. Preston continues to be actively involved in a number of studies of the long-term health effects of radiation, including studies in the Russian Federation, Japan, and the United States.

David Richardson (committee member, presenter, and session moderator) is Associate Professor of Epidemiology in the School of Public Health at the University of North Carolina at Chapel Hill. His research focuses on the health effects of occupational and environmental exposures, particularly with regard to ionizing radiation. He has conducted studies of cancer among nuclear workers in the United States and abroad, as well as studied cancer among the Japanese survivors of the atomic bombings of Hiroshima and Nagasaki. He has served as a visiting scientist at the World Health Organization’s International Agency for Research on Cancer, the French Institute for Radiological Protection and Nuclear Safety, and the Radiation Effects Research Foundation in Hiroshima, Japan. Since 2007, he has served as Director of the National Institute of Occupational Safety and Health–funded training program in occupational epidemiology at the University of North Carolina at Chapel Hill. In addition, he is a core faculty member at the Injury Prevention Research Center at the University of North Carolina, and a member of the Exposure and Biomarkers Research Core at the University’s Center for Environmental Health and Susceptibility. He is an Associate Editor of the journals Occupational and_Environmental Medicine, American Journal of Epidemiology, and Environmental Health Perspectives, and is a member of the President’s Advisory Board on Radiation and Worker Health. Dr. Richardson’s current research includes studies of mortality among nuclear industry workers and uranium miners, and development of innovative methods for occupational cancer studies. Dr. Richardson received a Ph.D. and an M.S.P.H., both in epidemiology, from the University of North Carolina.

Since July 2015, Dr. Andrew Scott (panelist) has served as the primary advisor on health-related nuclear and radiation issues to the Chief Medical Officer of the Department of Homeland Security (DHS). Prior to his work at DHS, he served as a U.S. Army Health Physicist for 19 years in a number of administrative and operational capacities. He earned his Ph.D. from Clemson University in 2010 and became a Certified Health Physicist in 2013. Dr. Scott’s publications are in the areas of human radiation dose estimation, uranium mobility in the environment, radiation detection instrumentation, radon remediation, and environmental sampling and analysis.

Ignacia (Iggie) Tanaka, DVM, Ph.D. (presenter), is an Associate Senior Scientist with the Pathology Group of the Radiobiology Department at the Institute for Environmental Sciences (IES). Her current work mainly focuses on the pathology, neoplastic and non-neoplastic diseases, of mice chronically exposed to low dose rates of gamma-rays. Prior to joining IES, she worked with non-human primates at a contract research organization, Ina Research Philippines, Inc. She received her degree, doctor of veterinary medicine (DVM), from the University of the Philippines, an M.S. in ruminant nutrition from Obihiro University, Japan, and a doctor of veterinary science (Ph.D.) in comparative pathology from Hokkaido University, Japan.

Dr. Robert Ullrich (presenter) is the Chief of Research, Vice Chairman, and Executive Director at the Radiation Effects Research Foundation (RERF) in Hiroshima, Japan. Dr. Ullrich initially joined RERF as its Associate Chief of Research in November 2013. Before joining RERF, Dr. Ullrich was the John Sealy Distinguished Chair in Cancer Biology, Director of the Sealy Center for Cancer Biology, and Interim Director of the Cancer Center at the University of Texas Medical Branch in Galveston, Texas. Prior to that he was the Barbara Cox Anthony Distinguished Chair in Oncology at Colorado State University and Director of the Colorado State component of the University of Colorado Consortium Comprehensive Cancer Center. He is recognized internationally for his research on mechanisms and risks of cancer following exposure to ionizing radiation and for his scientific leadership of laboratory, academic, and medical programs. Dr. Ullrich received the Radiation Research Society’s Failla Award in 2012 for outstanding research contributions in radiation science.

Alan E. Waltar (panelist), past President of the American Nuclear Society, recently retired as Director of Nuclear Energy at the Pacific Northwest National Laboratory after previously retiring as professor and head of the Department of Nuclear Engineering at Texas A&M. He holds a Ph.D. in engineering science from the University of California, Berkeley. Whereas the bulk of his career focused on fast reactor research and development, he is now focusing on potential upgrades to low dose radiation protection standards. This interest grew out of the unintended consequences of applying the current, ultra-conservative standards and the associated ethical issues.

Gayle Woloschak, Ph.D. (committee member, presenter, and session moderator), Professor in the Feinberg School of Medicine Departments of Radiation Oncology, Radiology and Cell and Molecular Biology, is currently involved in nine federally funded research studies, acting as the Principal Investigator on five of them. A renowned scientist, Dr. Woloschak has published numerous articles in journals like Molecular Immunology, Natures

Materials, and Proceedings of the National Academy of Sciences, and has her name registered on a long list of inventions. Woloschak has numerous faculty appointments at universities across the world. In addition to her roles at Northwestern, she is also a visiting scientist at the Bundeswehr Institute for Radiobiology in Munich, Germany; lecturer at Rosalind Franklin Medical School in North Chicago, Illinois; and visiting professor at Alexandria University in Alexandria, Egypt. Dr. Woloschak is co-leader of the Cancer Nano Materials Program in the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, and is a member of the Center for Genetic Medicine, and the Northwestern Comprehensive Center on Obesity. Dr. Woloschak is Associate Director of the Radiation Oncology Residency Program at Northwestern and was the recipient of this program’s Teacher of the Year Award during the 2005–2006 academic year. Recently, Dr. Woloschak’s teaching abilities were recognized again when she was awarded the 2010 Rosalind Franklin University Outstanding College of Health Professions Educator Award.