Advancing Research on Chronic Conditions in Women (2024)

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Appendix A Committee Member and Staff Biographies Eve J. Higginbotham, M.D., S.M., M.L. (Chair), is the former vice dean for inclusion, diversity, and equity of Penn Medicine at the University of Pennsylvania. She is also a senior fellow at the Leonard Davis Institute for Health Economics and at the Scheie Eye Institute. She is a glaucoma specialist and is active in scholarship related to glaucoma, ocular pharmacology, health policy, health equity, and organizational culture. Dr. Higginbotham was president of the Alpha Omega Alpha Honor Medical Society and a member of the Harvard Board of Overseers and the MIT Corporation. She serves on the two visiting committees at MIT, the Institute of Medical Engineering, and Science and Undergraduate and Graduate Student Life. She currently is on the board of directors of Ascension, a member of the executive and audit committees, and chair of the quality committee for the system. Dr. Higginbotham also serves on the board of the Massachusetts Eye and Ear in Boston. She serves as an associate editor on the editorial board of the American Journal of Ophthalmology. Dr. Higginbotham received her S.B. and S.M. degrees in chemical engineering at the Massachusetts Institute of Technology, M.D. from Harvard University, completed her residency in ophthalmology at the Louisiana State University Eye Center, and has a Master in Law from the University of Pennsylvania Carey Law School. She has been a member of the National Academy of Medicine (NAM) since 2000, serving on the National Academies of Science, Engineering, and Medicine consensus committees, previously serving on the National Academies Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities, currently on the Roundtable on Mentorship, Well-Being, and Professional Development. She recently chaired the consensus study, “The Impact of COVID-19 on the Careers of Women in Academic Sciences, Engineering, and Medicine.” She is also served as an elected member of the National Academy of Medicine Council and served as chair of the finance committee; in addition, she served on the governing board of the National Research Council, was a member of its strategic planning committee, and represented the NAM on the NAS investment committee, the classified and controlled activities committee, and the NRC governing board risk committee. She continues to publish papers in the areas focused on ophthalmology, health policy, and health equity. Arthur P. Arnold, Ph.D., is a distinguished research professor in the Department of Integrative Biology & Physiology at University of California, Los Angeles. He studies mechanisms causing PREPUBLICATION COPY: UNCORRECTED PROOFS 

2 ADVANCING RESEARCH ON CHRONIC CONDITIONS IN WOMEN sex differences in physiology and disease. His research has included discovering large structural sexual dimorphisms in the central nervous system, developing animal models for studying sex differences, and identifying the mechanisms by which sex-biasing factors operate in tissues, including sex chromosome effects. Dr. Arnold is a fellow of the AAAS and John Simon Guggenheim Memorial Foundation. He was the founding president of the Society of Behavioral Neuroendocrinology, which honored him with the Lehrman Lifetime Achievement Award in 2010. He co-founded the Organization for the Study of Sex Differences and was the founding editor-in-chief of its journal, Biology of Sex Differences. Dr. Arnold received his A.B. in psychology from Grinnell College and Ph.D. in neurobiology and behavior from Rockefeller University. His publications are related to factors that cause sex differences in physiology and disease in mice, rats, and songbirds, and he has written extensively about the design and interpretation of experiments in this area. Cynthia M. Boyd, M.D., M.P.H., is the Mason F. Lord Professor of Medicine and director of the Division of Geriatric Medicine and Gerontology, with joint appointments in epidemiology, and health policy and management at Johns Hopkins University. She is a practicing primary care physician and geriatrician at Johns Hopkins Bayview Medical Center and clinical researcher who has devoted her career to improving the health and health care of older adults with multiple chronic conditions (MCC). Dr. Boyd is an elected member of the American Society for Clinical Investigation. She was honored with the American Geriatric Society (AGS) Outstanding Scientific Achievement for Clinical Investigation Award in 2010. Dr. Boyd received her M.D. from Duke University. She was on the committee for the 2020 National Academies report on “Social Isolation and Loneliness in Older Adults: Opportunities for the Health Care System,”. Dr. Boyd has served in a compensated role for AGS on programs related to MCC and has co- authored a chapter on MCC for UptoDate. Nkechi T. Conteh, M.B.B.S., M.P.H., is a staff psychiatrist in the Department of Psychiatry at the Boston University Medical Center, program director for the Boston University Medical Center Psychiatry Residency Program, and assistant professor of Psychiatry at the Boston University School of Medicine. Dr. Conteh received n M.B.B.S. from the University of Ibadan in Nigeria. and completed her psychiatry residency at Duke University Hospital and health M.P.H. at the Harvard TH Chan School of Public Health (Harvard Chan). Dr Conteh’s residency experience was distinguished by her design and implementation of an EPIC perinatal psychiatry referral system that provided referring clinicians with culturally responsive prompts to promote engagement with psychiatric care, resulting in a four-fold increase in psychiatric postpartum follow-up. She received the Duke Department of Psychiatry Carter Community Service Award in recognition of her work. She was awarded the American College of Psychiatry Laughlin Fellowship, Group for Advancement of Psychiatry Fellowship, and Association of Women Psychiatrists International Fellowship for her international maternal mental health research. Dr. Conteh’s dedication to diversity and equity in psychiatry is evident in her previous role as the associate program director for diversity and equity in the MGH/McLean Psychiatry Residency Program. Her initiatives include developing a mentorship workshop for underrepresented in medicine residents and faculty, creating a health disparities research track, and an immigrant and refugee mental health elective. She also directed a collaborative perinatal psychiatry community clinic at Massachusetts General Hospital (MGH). Her publications span a wide range of topics, including ethnic identity, medical mistrust, global mental health, and racial disparities in PREPUBLICATION COPY: UNCORRECTED PROOFS 

APPENDIX A 3 perinatal care. Dr. Conteh's contributions have been recognized with the 2022 Clinician Teacher Development Award from the MGH Center for Diversity, 2022 MGH Global Health Community Engagement Award, and 2023 American Board of Psychiatry and Neurology (ABPN) Faculty Innovation in Education Award. Kristine Y. DeLeon-Pennell, Ph.D., is an associate professor of cardiology at the Medical University of South Carolina (MUSC) and a research health scientist at the Ralph H Johnson VA Medical Systems. Her work focuses on the inflammatory and fibrotic components of cardiac remodeling following a heart attack. Her major research interests include how pre-existing conditions such as sex, age, and stress regulate inflammation and cardiac healing. She has received more than 30 awards, including the UMMC chapter of the Group on Women in Medicine and Science Emerging Star Award. Dr. DeLeon-Pennell has served on committees for the American Physiological Society (APS) and the American Heart Association (AHA), including the APS awards committee (Cardiovascular Section) and the communications committee for AHA’s Council on the Kidney in Cardiovascular Disease Section. She is consulting editor for the American Journal of Physiology–Heart and Circulatory Physiology and on the editorial board for the Biology of Sex Differences Journal. Dr. DeLeon-Pennell received her Ph.D. from Baylor University in biomedical studies and completed postdoctoral fellowships at the University of Texas Health Science Center at San Antonio and the University of Mississippi Medical Center in Jackson. She published two guideline articles in the American Journal of Physiology –Heart and Circulatory Physiology in 2021 on the importance of evaluating both sexes in clinical and basic research. Erica E. Marsh, M.D., M.S.C.I., F.A.C.O.G., is Vice Chair of the Department of Obstetrics and Gynecology and chief of the Division of Reproductive Endocrinology and Infertility at the University of Michigan Medical School. She holds the university professor of Diversity and Social Transformation at the University of Michigan, and the S. Jan Behrman Collegiate Professor of Reproductive Medicine at its medical school and is the associate director of the Michigan Institute for Clinical and Health Research. Dr. Marsh’s work focuses on comparative reproductive health across populations. She applies a translational lens to her research, by addressing the pathophysiology of disease, social determinants of health, the patient experience, and community impact. Her studies include the areas of uterine fibroids, abnormal uterine bleeding, ovarian reserve/infertility, and disparities in reproductive health. Dr. Marsh received the Ira and Esther Rosenwaks New Investigator Award from the American Society of Reproductive Medicine and has been elected to the American Gynecological and Obstetrical Society and American Society of Clinical Investigation. Dr. Marsh received her B.A. in sociology from Harvard College and M.D. from Harvard Medical School. She completed her OB/GYN residency at the Brigham and Women’s Hospital and Massachusetts General Hospital and her fellowship in reproductive endocrinology and infertility at the Feinberg School of Medicine at Northwestern University. Dr. Marsh was a consultant for Alnylam, Myovant Sciences and Pfizer, receiving compensation for these services. She has shared social media posts on uterine fibroids and other women’s health issues and has published numerous articles on uterine fibroids and reproductive health issues within the last 5 years. Stacey A. Missmer, Sc.D., is a professor of obstetrics and gynecology at the University of Michigan, an adjunct professor of obstetrics and gynecology at Michigan State University, an PREPUBLICATION COPY: UNCORRECTED PROOFS 

4 ADVANCING RESEARCH ON CHRONIC CONDITIONS IN WOMEN adjunct professor of epidemiology at Harvard T.H. Chan School of Public Health (Harvard Chan), and a lecturer in pediatrics at Harvard Medical School. Her research has focused on causes, consequences, and the discovery of modifiable factors related to reproductive health and identified in utero exposures, early-life body size, and dietary intake as risk factors for endometriosis, and has established those with endometriosis as a high-risk group for cancers and immune and cardiovascular diseases. She is the senior endometriosis investigator in the Nurses’ Health Study Research Group and co-founded the Boston Center for Endometriosis in 2012, where she designed and leads the Women’s Health Study: from Adolescence to Adulthood. She is also the co-principal investigator (co-PI) of the World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project and the USA-PI for the International Endometriosis Genomics Consortium. In May 2023, she became president of the World Endometriosis Society. She previously served as faculty lead for the Reproductive, Perinatal and Pediatric Epidemiology concentration at Harvard Chan, both director of epidemiologic research and fellowship research director for the Division of Reproductive Medicine at Brigham and Women’s Hospital, and a member of the Data Safety and Monitoring Board of the NIH Reproductive Medicine Network. Dr. Missmer received her B.A. in Biology from Lehigh University and her M.S and Sc.D. degrees in Epidemiology from Harvard School of Public Health. Dr. Missmer has offered her expert opinions on needs for endometriosis-related scientific discovery as a past member of advisory boards for Roche and AbbVie, LLC., and a participant in a 2022 roundtable hosted by Abbott Laboratories and 2023 LIDEAR advisor hosted by ZEG Berlin. She is the field chief editor for Frontiers in Reproductive Health. Dr. Missmer co-authored a review of the state of science for endometriosis in the New England Journal of Medicine in 2020, a review of its state of the science and standards for clinical care for endometriosis in the British Medical Journal in 2022, and a commentary on global prioritization for endometriosis in Nature Communications in 2023. Anna Camille J. Moreno, D.O., N.C.M.P., is assistant professor in the Department of Obstetrics and Gynecology at University of Utah and the medical director of the Midlife Women’s Health and Menopausal Medicine program. She is a certified North American Menopause Society menopause provider. Her research interests span menopause, menopausal hormone therapy, perimenopause, medical management and risk assessment of menopausal symptoms of patients with hereditary breast and ovarian cancer and those at high risk, optimization of medical care and cardiovascular risk stratification in menopause/perimenopause, midlife weight management, genitourinary syndrome of menopause and other midlife vulvar dermatoses and vulvovaginitis, bone management; sexual health and dysfunction management; and contraception specifically in those with health risks and chronic diseases. Her past work includes a case study of vulvar Crohn disease, a retrospective evaluation of the use of high-risk, potentially teratogenic medications in women of childbearing age, and a cost-comparison analysis of a pelvic floor neuromodulation device. Dr. Moreno is currently an associate editor of Utah Women’s Health Review and a peer reviewer for American Family Physician. She received her D.O. from Edward Via College of Osteopathic Medicine. She was also a consultant for Astellas Pharma and a medical writer for GoodRx, receiving compensation for these services. Walter A. Rocca, M.D., M.P.H., is a professor of epidemiology and neurology and the Ralph S. and Beverley E. Caulkins Professor of Neurodegenerative Diseases Research at the Mayo Clinic College of Medicine and Science in Rochester, Minnesota. He is codirector of the Rochester PREPUBLICATION COPY: UNCORRECTED PROOFS 

APPENDIX A 5 Epidemiology Project medical records-linkage system, associate director of the Specialized Center of Research Excellence on Sex Differences, and a member of the Steering Group for the Mayo Clinic Women’s Health Research Center. His research focuses on brain aging and the etiology of common neurodegenerative diseases, such as Parkinsonism and dementia. In particular, Dr. Rocca has studied the effects of surgical menopause on brain aging and multimorbidity as a clinical marker of accelerated aging. Dr. Rocca has been member of the Science Committee of the American Academy of Neurology and served on several expert panels for the NIH and for other institutions nationally (including the IOM) and internationally. He served on the Cross-Cutting Sex and Gender Review Group for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR). He serves on the Observational Study Monitoring Board for the project Reasons for Geographic and Racial Differences in Stroke funded by the National Institute of Neurological Disorders and Stroke and on the Premature Ovarian Insufficiency Guideline Development Group, European Society for Human Reproduction and Embryology. He served on the editorial board of two journals related to women’s health, Menopause and Maturitas. Dr. Rocca received his M.D. from the University of Padua, Italy, Diploma of Specialty in Neurology from the University of Verona, Italy, M.P.H. from the Johns Hopkins University, School of Hygiene and Public Health, and completed postdoctoral fellowships at the Johns Hopkins University and at the National Institute of Neurological Disorders and Stroke. Julia Fridman Simard, Sc.D., is an associate professor of epidemiology & population health, and of medicine in immunology and rheumatology and, by courtesy, obstetrics and gynecology in maternal fetal medicine at Stanford University School of Medicine. She studies autoimmune diseases, particularly conditions disproportionately diagnosed in women. Topics of her research include rheumatoid arthritis, systemic lupus, systemic sclerosis and maternal and fetal outcomes in lupus pregnancies. She also has experience with pharmaco-, reproductive, and perinatal epidemiology, clinical outcomes including cancer and stroke, and a range of research methods. Dr. Simard is a member of the American College of Rheumatology/Association of Rheumatology Professional (ACR/ARP), Society for Pediatric and Perinatal Epidemiologic Research, and the Society for Epidemiologic Research. She is on the editorial board of Arthritis Care & Research, associate editor at ACR Open Rheumatology, completed the Pediatric and Perinatal Epidemiology’s Junior Editor program (2019–2022), and served as co-editor of a special issue on methodologic considerations of big data research in reproductive and perinatal epidemiology. Dr. Simard earned her B.A. in mathematics–applied science at the University of California at San Diego, and her SM and Sc.D. degrees in epidemiology at the Harvard School of Public Health. She completed her post-doctoral fellowship in clinical epidemiology at the Karolinska Institute in Stockholm. She serves in an uncompensated role on the Scientific Advisory Board for Metrodora Foundation and previously on the Honorary Medical Advisory Board, and Lupus and Allied Diseases Association. Dr. Simard worked with the Global Rheumatology Alliance to develop and implement a patient-facing COVID vaccine survey and received compensation for this activity. She is also a past member of the systemic lupus erythematosus (SLE) Curriculum Review Committee, Collaborative Initiatives with the ACR and the Global Rheumatology Alliance’s RheumCovid, initiative. Dr. Simard has also worked with ACR in multiple capacities including on the Voting Panel (2017–2019) of the Reproductive Health Guidelines working group, which released recommendations on management of rheumatic disease during pregnancy. PREPUBLICATION COPY: UNCORRECTED PROOFS 

6 ADVANCING RESEARCH ON CHRONIC CONDITIONS IN WOMEN Farida Sohrabji, Ph.D., is a university distinguished professor and department head of neuroscience and experimental therapeutics at Texas A&M University. Her research focuses on the pathophysiology of ischemic stroke, a leading risk factor for Alzheimer’s Disease and related dementia and developing novel treatments. Her work has shown that estrogen treatment in older acyclic females was not neuroprotective for stroke and also that stroke neuroprotectants may be effective in only one sex. Dr. Sohrabji is a TAMU Regents Professor, fellow of the American Heart Association (Stroke Council), fellow of the International Behavioral Neuroscience Society, and an inaugural Texas A&M Presidential Impact Fellow. She is the current holder of the John and Maurine Cox Endowed Chair. Dr. Sohrabji is founder and Director of the Women’s Health in Neuroscience Program and a strong advocate for including gender/sex differences in biomedical research. Dr. Sohrabji obtained her Ph.D. in neuroscience/biopsychology from the University of Rochester and completed her postdoctoral training at Columbia University. She is on the External Advisory Committee for the NIH-funded Centers of Biomedical Research Excellence grants at Tulane University School of Medicine and West Virginia University and receives compensation for these services. Dr. Sohrabji has presented a webinar for NIH’s Office of Research in Women’s Health on sex difference in neurology in 2020 and published numerous articles related to sex differences in stroke risk and severity in the last 5 years. Sandra Springer, M.D., is a professor of medicine in the department of internal medicine, section of infectious diseases at the Yale University School of Medicine and an attending physician at the Veterans Administration Connecticut Healthcare System and directs the Veterans Administration Newington, CT Infectious Disease Clinic. She is the director of Integrating Substance Use Treatment Research with Infectious Disease treatment for Everyone at the Yale School of Medicine where she conducts clinical research on the integration of substance use disorders and infectious disease/HIV prevention and treatments. She has focused on evaluating medication treatments for opioid and alcohol use disorders to improve them for persons involved with the criminal justice system. Dr. Springer was awarded the prestigious National Institute of Drug Abuse Director’s Pioneer Award/Avant Garde Award. She is a member of the International Antiviral Society–USA Antiretroviral Guidelines Committee, American Society of Addiction Medicine (ASAM) committees for Jail Withdrawal Guidelines partnering with the Bureau of Justice Agency and ASAM’s Criminal Justice Guideline Committee, and the Infectious Disease Society of America. She served as a member of ASAM’s Focused Update Guideline committee on the Treatment of Opioid Use Disorder. Dr. Springer received her A.B. from Harvard University and M.D. from the University of Massachusetts Medical School and completed her internal medicine residency and fellowship in infectious disease at Yale University School of Medicine. She was on the National Academies Committee on the Examination of the Integration of Opioid and Infectious Disease Prevention Efforts in Select Programs 2019–2020. Dr. Springer was a consultant for Alkermes Inc. and received compensation for this activity. STAFF Aisha Bhimla, Ph.D., M.P.H., is a program officer in the Health and Medicine Division at the National Academies of Sciences, Engineering, and Medicine. Earlier, Dr. Bhimla was a health quantitative senior analyst at Abt Associates, providing support to various PREPUBLICATION COPY: UNCORRECTED PROOFS 

APPENDIX A 7 federally/internationally funded health-related projects. She completed a postdoctoral fellowship at the Center for Asian Health at Temple University Lewis Katz School of Medicine (2020– 2022), where she facilitated and conducted epidemiological and community-based research studies on chronic disease and cancer, physical activity, cognitive functioning, and teen pregnancy/STI prevention in racially and ethnically minoritized populations. Her specific research focused on neighborhood and built environmental factors and their association with lifestyle factors and chronic health conditions. Her research findings have been published in multiple journals, such as Preventing Chronic Disease, Journal of Racial and Ethnic Health Disparities, and Journal of Community Health. She is a board member (research co-chair) with the South Asian Public Health Association. She obtained a Ph.D. in kinesiology from Temple University, and a M.P.H. at the University of South Florida. Zarah Batulan, Ph.D., is an associate program officer in the Health and Medicine Division at the National Academies of Sciences, Engineering, and Medicine. Earlier, Dr. Batulan was the research manager for a cardiac science laboratory at the University of Calgary in Alberta, Canada, where she managed multiple research and clinical studies on cardiovascular disease. Dr. Batulan received her Ph.D. in neuroscience from McGill University in Montreal, Quebec, Canada, studying the neurodegenerative disease, amyotrophic lateral sclerosis. She completed a Group d’Étude des Protéines Membranaires (GÉPROM) postdoctoral fellowship in biophysics at the Université de Montréal focusing on structure-function studies of potassium channels and how certain mutations are linked to the motor disorder, episodic ataxia type 1. Donna Almario Doebler, Dr.P.H., M.S., M.P.H., is a senior program officer at the National Academies of Sciences, Engineering, and Medicine (the National Academies). She is part of the Health and Medicine Division’s Board on Population Health and Public Health Practice. Prior to joining the National Academies, Dr. Doebler was the associate vice president of Medicare Advantage at UPMC Health Plan in Pittsburgh, PA, where she led product, strategy, and financial and clinical analytics to help manage the care of over 200,000 member lives. In addition, she worked with UPMC hospitals to develop the first community health needs assessments and implementation plans, as part of new ACA requirements for all nonprofit hospitals. She was also an assistant professor at the University of Pittsburgh Graduate School of Public Health, served as a biostatistician at Veterans Administration Pittsburgh Health System’s Center for Health Equity Research and Promotion, and worked at the Institute of Medicine and the U.S. Government Accountability Office. Dr. Doebler completed a Kellogg Health Scholars postdoctoral fellowship and has a Dr.PH. in behavioral and community health sciences, an M.S. in biostatistics—both from the University of Pittsburgh, and an M.P.H. in epidemiology from the George Washington University. Her focus is on achieving health equity and understanding the social, community, and contextual factors that impact population health, especially with the aging population. Amy Geller, M.P.H., is a senior program officer at the National Academies of Sciences, Engineering, and Medicine (the National Academies) in the Health and Medicine Division (HMD) on the Board on Population Health and Public Health Practice. At the National Academies, she has staffed committees spanning many topics, including advancing health equity, prevention of sexually transmitted infections, reducing alcohol-impaired driving fatalities, workforce resilience, vaccine safety, reducing tobacco use, drug safety, and treating post- PREPUBLICATION COPY: UNCORRECTED PROOFS 

8 ADVANCING RESEARCH ON CHRONIC CONDITIONS IN WOMEN traumatic stress disorder. She was and is the study director, respectively, for the recently released HMD report Federal Policy to Advance Racial, Ethnic, and Tribal Health and the HMD Committee on the Assessment of NIH Research on Women's Health. She also directs the DC Public Health Case Challenge, a joint activity of HMD and the National Academy of Medicine that aims to promote interdisciplinary, problem-based learning for college students at universities in the DC area. Grace Reading, B.S., is a senior program assistant at the National Academies of Sciences, Engineering, and Medicine in the Health and Medicine Division on the Board of Population Health and Public Health Practice. She graduated from the University of Kansas with a B.S.in marketing and a minor in women, gender, and sexuality studies. Mia Saltrelli, B.S., is a senior program assistant at the National Academies of Sciences, Engineering, and Medicine in the Health and Medicine Division on the Board of Population Health and Public Health Practice. She graduated from Furman University with a B.S. in public health. Rose Marie Martinez, Sc.D., has been the senior board director of the Board on Population Health and Public Health Practice (BPH) at the National Academies of Sciences, Engineering, and Medicine (the National Academies) since 1999. BPH addresses the science base for population health and public health interventions and examines the capacity of the health system, particularly the public health infrastructure, to support disease prevention and health promotion activities, including the education and supply of health professionals necessary for carrying them out. BPH has examined such topics as the safety of childhood vaccines and other drugs, systems for evaluating and ensuring drug safety post-marketing, the health effects of cannabis and cannabinoids, the health effects of environmental exposures, population health improvement strategies, the integration of medical care and public health, women’s health services, health disparities, health literacy, tobacco control strategies, and chronic disease prevention, among others. Dr. Martinez was awarded the 2010 Institute of Medicine (IOM) Research Cecil Award for significant contributions to IOM reports of exceptional quality and influence. Before joining the National Academies, Dr. Martinez was a senior health researcher at Mathematica Policy Research (1995–1999), where she conducted research on the impact of health system change on public health infrastructure, access to care for vulnerable populations, managed care, and the health care workforce. Dr. Martinez is a former assistant director for health financing and policy with the U.S. General Accountability Office, where she directed evaluations and policy analysis in the area of national and public health issues (1988–1995). Her experience also includes 6 years directing research studies for the Regional Health Ministry of Madrid, Spain (1982–1988). Dr. Martinez was a member of the Council on Education for Public Health, the accreditation body for schools of public health and public health programs. She received a Sc.D. from the Johns Hopkins School of Hygiene and Public Health. PREPUBLICATION COPY: UNCORRECTED PROOFS