Tenth Interim Report of the Subcommittee on Acute Exposure Guideline Levels (2004)

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TENTH INTERIM REPORT OF THE SUBCOMMITTEE ON ACUTE EXPOSURE GUIDELINE LEVELS 4 Page A-1. Add the calculation for a 10-min AEGL-1, as it is missing. Minor Issues In the AEGL derivations, the subcommittee recommends using ppm-hr and the SOP manual recommended significant figure issues. Use line numbering. Section 5.3, 2nd paragraph. Does the discussion on geometric mean contain the proper terminology and rationale? As 3.16 is the square root of 10, which makes it the geometric mean—but is that the reason a UF of 3.16 is used here? This is the first time it has been discussed and this is commended, but the rationale must be clear and understandable. Editorial Comments Add “planners and” before “responders” in all the LOA discussions. There are a number of blank pages. Section 4.4.3, 2nd line add “be” after “may”. Section 6.2, 1st paragraph, end of penultimate line change “question” to “questionable” and add “use”. Table 15. Spell out STPL. There are format problems with the carcinogenicity assessment section. Provide separate animal and human category plots. It is recommended that the NAC combine sections on odor threshold and LOA. These data are now separated and that format is confusing. Increase font size in Section B-1 for the equations. COMMENTS ON ETHYLENE OXIDE At its July 21–23, 2003 meeting, the subcommittee reviewed the revised AEGL document on ethylene oxide. The document was presented by Kowetha Davidson of Oak Ridge National Laboratory. The subcommittee recommends a number of revisions. The document can be finalized if the subcommittee's recommended revisions are appropriately made.