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Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field (2023)

Chapter: Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research

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Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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D

Decision Tree for the Use of Population Descriptors in Genomics Research

Page 194 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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FIGURE D-1 Decision tree for the use of population descriptors in genomics research. The decision tree follows on the next several pages.
Page 195 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 196 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 197 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 198 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 199 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 200 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 201 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 202 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 193 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 194 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 195 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 196 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 197 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Page 200 Cite
Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Suggested Citation:"Appendix D:Decision Tree for the Use of Population Descriptors in Genomics Research." National Academies of Sciences, Engineering, and Medicine. 2023. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. Washington, DC: The National Academies Press. doi: 10.17226/26902.
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Genetic and genomic information has become far more accessible, and research using human genetic data has grown exponentially over the past decade. Genetics and genomics research is now being conducted by a wide range of investigators across disciplines, who often use population descriptors inconsistently and/or inappropriately to capture the complex patterns of continuous human genetic variation.

In response to a request from the National Institutes of Health, the National Academies assembled an interdisciplinary committee of expert volunteers to conduct a study to review and assess existing methodologies, benefits, and challenges in using race, ethnicity, ancestry, and other population descriptors in genomics research. The resulting report focuses on understanding the current use of population descriptors in genomics research, examining best practices for researchers, and identifying processes for adopting best practices within the biomedical and scientific communities.

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